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This antibody recognizes a major 39 kDa band of endogenous STX12. In some cases, two additional bands of 33 kDa and 66 kDa could also be detected, which most likely represent a degradation product and a SNARE complex respectively.
Immunogen sequence: MSYGPLDMY RNPGPSGPQL RDFSSIIQTC SGNIQRISQA TAQIKNLMSQ LGTKQDSSKL QENLQQLQHS TNQLAKETNE LLKELGSLPL PLSTSEQRQQ RLQKERLMND FSAALNNFQA VQRRVSEKEK ESIARARAGS RLSAEERQRE EQLVSFDSHE EWNQMQSQED EVAITEQDLE LIKERETAIR QLEADILDVN QIFKDLAMMI HDQGDLIDSI EANVESSEVH VERATEQLQR AAYYQKKSRK KMCIL (1-254 aa encoded by BC046999)
SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC51957; Syn13; syntaxin 13; Syntaxin-12; Syntaxin-13
Gene Aliases: AI850350; AU041521; STX12; STX13; STX14
UniProt ID: (Human) Q86Y82, (Rat) G3V7P1, (Mouse) Q9ER00
Entrez Gene ID: (Human) 23673, (Rat) 65033, (Mouse) 100226
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