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Proteintech
Syntaxin 1A/Syntaxin 1B Monoclonal Antibody (2D3B5), CoraLite® 594
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Product Details
CL59466437100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2D3B5
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adipocyte; adiponectin; FP17469; HGNC:11433; Neuron-specific antigen HPC-1; P35A; P35B; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin 1B1; syntaxin 1B2; Syntaxin 2; syntaxin a/b; Syntaxin-1A; Syntaxin-1B; Syntaxin-1B1; Syntaxin-1B2
Gene Aliases: GEFSP9; HPC-1; P35-1; Sap; STX1; STX1A; STX1B; STX1B1; STX1B2; Stx1bl; Stx2; SYN1A; Syn1b
UniProt ID: (Human) Q16623, (Human) P61266, (Mouse) O35526, (Rat) P32851, (Mouse) P61264, (Rat) P61265
Entrez Gene ID: (Human) 6804, (Human) 112755, (Mouse) 20907, (Rat) 116470, (Mouse) 56216, (Rat) 24923
SNARE binding
glycoprotein binding
SNAP receptor activity
protein binding
myosin binding
calcium channel inhibitor activity
chloride channel inhibitor activity
kinase binding
protein domain specific binding
protein binding, bridging
myosin head/neck binding
ATP-dependent protein binding
ion channel binding
protein heterodimerization activity
protein N-terminus binding
calcium-dependent protein binding
protein kinase binding
positive regulation of neurotransmitter secretion
transport
neurotransmitter transport
intracellular protein transport
exocytosis
regulation of gene expression
regulation of synaptic vesicle priming
protein transport
synaptic vesicle docking
vesicle-mediated transport
regulation of exocytosis
synaptic vesicle fusion to presynaptic active zone membrane
spontaneous neurotransmitter secretion
positive regulation of excitatory postsynaptic potential
response to gravity
positive regulation of norepinephrine secretion
calcium ion regulated exocytosis
secretion by cell
positive regulation of catecholamine secretion
positive regulation of exocytosis
positive regulation of calcium ion-dependent exocytosis
vesicle docking
neurotransmitter secretion
glutamate secretion
regulation of insulin secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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