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TACO1/CCDC44 Polyclonal Antibody

TACO1/CCDC44 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TACO1/CCDC44 Antibody (21147-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human kidney using 21147-1-AP (TACO1/CCDC44 antibody) at dilution of 1:50 (under 40x lens).

TACO1/CCDC44 Antibody in Western Blot (WB)

TACO1/CCDC44 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

21147-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 7 publications 7 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TACO1/CCDC44 Fusion Protein Ag15688 (1-297 aa encoded by BC007744)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSAWAAASL SRAAARCLLA RGPGVRAAPP RDPRPSHPEP RGCGAAPGRT LHFTAAVPAG HNKWSKVRHI KGPKDVERSR IFSKLCLNIR LAVKEGGPNP EHNSNLANIL EVCRSKHMPK STIETALKME KSKDTYLLYE GRGPGGSSLL IEALSNSSHK CQADIRHILN KNGGVMAVGA RHSFDKKGVI VVEVEDREKK AVNLERALEM AIEAGAEDVK ETEDEEERNV FKFICDASSL HQVRKKLDSL GLCSVSCALE FIPNSKVQLA EPDLEQAAHL IQALSNHEDV IHVYDNIE (1-297 aa encoded by BC007744)

Target Information

TACO1 is a mitochondrial translational activator required for efficient translation of cytochrome c oxidase (Weraarpachai et al., 2009), a component of complex IV of the mitochondrial respiratory complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

PET117 assembly factor stabilizes translation activator TACO1 thereby upregulates mitochondria-encoded cytochrome C oxidase 1 synthesis.

Free radical biology & medicine

Sun Q,Shi L,Li S,Li J,Zhang R,Huang X,Shao Y,Feng Z,Peng Y,Yang Z,Liu J,Liu H,Long J

Sun Aug 20 00:00:00 UTC 2023

PET117 assembly factor stabilizes translation activator TACO1 thereby upregulates mitochondria-encoded cytochrome C oxidase 1 synthesis.

Free radical biology & medicine

Sun Q,Shi L,Li S,Li J,Zhang R,Huang X,Shao Y,Feng Z,Peng Y,Yang Z,Liu J,Liu H,Long J

Sun Aug 20 00:00:00 UTC 2023

Muscle denervation reduces mitochondrial biogenesis and mitochondrial translation factor expression in mice.

Biochemical and biophysical research communications

Yokokawa T,Mori R,Suga T,Isaka T,Hayashi T,Fujita S

Thu Jun 18 00:00:00 UTC 2020

Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.

The EMBO journal

Ferreira N,Perks KL,Rossetti G,Rudler DL,Hughes LA,Ermer JA,Scott LH,Kuznetsova I,Richman TR,Narayana VK,Abudulai LN,Shearwood AJ,Cserne Szappanos H,Tull D,Yeoh GC,Hool LC,Filipovska A,Rackham O

Mon Dec 16 00:00:00 UTC 2019

Fidelity of translation initiation is required for coordinated respiratory complex assembly.

Science advances

Rudler DL,Hughes LA,Perks KL,Richman TR,Kuznetsova I,Ermer JA,Abudulai LN,Shearwood AJ,Viola HM,Hool LC,Siira SJ,Rackham O,Filipovska A

Sun Dec 01 00:00:00 UTC 2019

Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.

Physiological reports

Yokokawa T,Kido K,Suga T,Isaka T,Hayashi T,Fujita S

Mon Oct 01 00:00:00 UTC 2018

Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.

Physiological reports

Yokokawa T,Kido K,Suga T,Isaka T,Hayashi T,Fujita S

Mon Oct 01 00:00:00 UTC 2018

Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.

Nature communications

Richman TR,Spåhr H,Ermer JA,Davies SM,Viola HM,Bates KA,Papadimitriou J,Hool LC,Rodger J,Larsson NG,Rackham O,Filipovska A

Mon Jun 20 00:00:00 UTC 2016

Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.

Nature communications

Richman TR,Spåhr H,Ermer JA,Davies SM,Viola HM,Bates KA,Papadimitriou J,Hool LC,Rodger J,Larsson NG,Rackham O,Filipovska A

Mon Jun 20 00:00:00 UTC 2016

MicroRNA directly enhances mitochondrial translation during muscle differentiation.

Cell

Zhang X,Zuo X,Yang B,Li Z,Xue Y,Zhou Y,Huang J,Zhao X,Zhou J,Yan Y,Zhang H,Guo P,Sun H,Guo L,Zhang Y,Fu XD

Thu Jul 31 00:00:00 UTC 2014

MicroRNA directly enhances mitochondrial translation during muscle differentiation.

Cell

Zhang X,Zuo X,Yang B,Li Z,Xue Y,Zhou Y,Huang J,Zhao X,Zhou J,Yan Y,Zhang H,Guo P,Sun H,Guo L,Zhang Y,Fu XD

Thu Jul 31 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: clone HQ0477 PRO0477p; coiled-coil domain containing 44; Coiled-coil domain-containing protein 44; coiled-coil domain-containing protein 44 {ECO:0000312|EMBL:AAI66900.1}; taco1 {ECO:0000250|UniProtKB:Q9BSH4}; Translational activator of cytochrome c oxidase 1; translational activator of cytochrome c oxidase 1 {ECO:0000250|UniProtKB:Q9BSH4}; translational activator of mitochondrially encoded cytochrome c oxidase I; Translational activator of mitochondrially-encoded cytochrome c oxidase 1; Translational activator of mitochondrially-encoded cytochrome c oxidase I; translational activator of mitochondrially-encoded cytochrome c oxidase I {ECO:0000250|UniProtKB:Q9BSH4}

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Gene Aliases: 2310066I18Rik; CCDC44; PRO0477; RGD1306784; TACO1

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UniProt ID: (Human) Q9BSH4, (Rat) B2RYT9, (Mouse) Q8K0Z7

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Entrez Gene ID: (Human) 51204, (Rat) 360645, (Mouse) 70207

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Function(s)

molecular_function

Process(es)

regulation of translation biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TACO1/CCDC44 Polyclonal Antibody

TACO1/CCDC44 Antibody (21147-1-AP) in IHC (P)

Product Details

21147-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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