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Proteintech
TADA2L Polyclonal Antibody
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Product Details
11299-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TADA2L Fusion Protein Ag1817 (1-352 aa encoded by BC011753)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDRLGSFSN DPSDKPPCRG CSSYLMEPYI KCAECGPPPF FLCLQCFTRG FEYKKHQSDH TYEIMTSDFP VLDPSWTAQE EMALLEAVMD CGFGNWQDVA NQMCTKTKEE CEKHYMKHFI NNPLFASTLL NLKQAEEAKT ADTAIPFHST DDPPRPTFDS LLSRDMAGYM PARADFIEEF DNYAEWDLRD IDFVEDDSDI LHALKMAVVD IYHSRLKERQ RRKKIIRDHG LINLRKFQLM ERRYPKEVQD LYETMRRFAR IVGPVEHDKF IESHALEFEL RREIKRLQEY RTAGITNFCS ARTYDHLKKT REEERLKRTM LSEVLQYIQD SSACQQWLRR QADIDSGLSP SIP (1-352 aa encoded by BC011753)
Target Information
TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-alpha) or ADA2-like protein, is a 443 amino acid nuclear protein that exists as 2 alternatively spliced isoforms. While most abundantly expressed in testis, TADA2L is present in all tissues. TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows TADA2L to play a role in chromatin remodeling. Although it makes up part of the PCAF complex, TADA2L is also a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. The gene that encodes TADA2L contains 71,408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADA2-like protein; Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; transcriptional adaptor 2 alpha
Gene Aliases: ADA2; ADA2A; AV319371; D030022J10Rik; hADA2; KL04P; TADA2A; TADA2L
UniProt ID: (Human) O75478, (Rat) Q6AYE3, (Mouse) Q8CHV6
Entrez Gene ID: (Human) 6871, (Rat) 360581, (Mouse) 217031
regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
mitotic nuclear division
biological_process
regulation of histone deacetylation
regulation of protein stability
histone H3 acetylation
regulation of tubulin deacetylation
regulation of transcription from RNA polymerase II promoter
histone acetylation
chromatin remodeling
transcription from RNA polymerase II promoter
positive regulation of histone acetylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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