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Invitrogen
TAF13 Polyclonal Antibody
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Product Details
PA5-60728
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TAF13. Recombinant protein control fragment (Product #RP-89444).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2648187
Product Specific Information
Immunogen sequence: EDPTFEEENE EIGGGAEGGQ GKRKRLFSKE LRCMMYGFGD DQNPYTESVD ILEDLVIEFI TEMTHKAMSI GRQGRVQVED IVFLIRKDPR KFARVKDLLT MNEELKRA
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC22425; TAF(II)18; TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase II, K, 18kD; TATA box binding protein associated factor 13; transcription initiation factor TFIID 18 kD subunit; Transcription initiation factor TFIID 18 kDa subunit; Transcription initiation factor TFIID subunit 13
Gene Aliases: TAF(II)18; TAF13; TAF2K; TAFII-18; TAFII18
UniProt ID: (Human) Q15543
Entrez Gene ID: (Human) 6884
DNA-templated transcription, initiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
snRNA transcription from RNA polymerase II promoter
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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