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Immunogen sequence: MDLEESEEF KERCTQCAAV SWGLTDEGKY YCTSCHNVTE RYQEVTNTDL IPNTQIKALN RGLKKKNNTE KGWDWYVCEG FQYILYQQAE ALKNLGVGPE LKNDVLHNFW KRYLQKSKQA YCKNPVYTTG RKPTVLEDNL SHSDWASEPE LLSDVSCPPF LESGAESQSD IHTRKPFPVS KASQSETSVC SGSLDGVEYS QRKEKGIVKM TMPQTLAFCY LSLLWQREAI TLSDLLRFVE EDHIPYINAF QHFPEQMKLY GRDRGIFGIE SWPDYEDIYK KTIEVGTFLD LPRFPDITED CYLHPNILCM KYLMEVNLPD EMHSLTCHVV KMTGMGEVDF LTFDPIA (1-346 aa encoded by BC018137)
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during trancription initiation such as preinitiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RNA polymerase I-specific TBP-associated factor 63 kDa; SL1, 63kD subunit; TAFI63; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa; TATA box binding protein associated factor 1B; TATA box-binding protein-associated factor 1B; TATA box-binding protein-associated factor RNA polymerase I subunit B; TATA-box binding protein associated factor, RNA polymerase I, B; TBP-associated factor 1B; Transcription initiation factor SL1/TIF-IB subunit B
Gene Aliases: MGC:9349; RAF1B; RAFI63; SL1; TAF1B; TAFI63
UniProt ID: (Human) Q53T94
Entrez Gene ID: (Human) 9014
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