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Abnova
TAF1C Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
TAF1C Antibody (H00009013-D01P) in WB
Western Blot analysis of TAF1C expression in transfected 293T cell line (H00009013-T01) by TAF1C MaxPab polyclonal antibody.
Lane 1: TAF1C transfected lysate(85.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: TAF1C transfected lysate(85.10 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00009013-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TAF1C (AAH28131.1, 1 a.a. approximately 775 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MLPPLIDPWD PGLTARDLLF RGGYRYRKRP RVVLDVTEQI SRFLLDHGDV AFAPLGKLML ENFKLEGAGS RTKKKTVVSV KKLLQDLGGH QPWGCPWAYL SNRQRRFSIL GGPILGTSVA SHLAELLHEE LVLRWEQLLL DEACTGGALA WVPGRTPQFG QLVYPAGGAQ DRLHFQEVVL TPGDNPQFLG KPGRIQLQGP VRQVVTCTVQ GETLLAVRSD YHCAVWKFGK QWQPTLLQAM QVEKGATGIS LSPHLPGELA ICSRSGAVCL WSPEDGLRQI YRDPETLVFR DSSSWRWADF TAHPRVLTVG DRTGVKMLDT QGPPGCGLLL FRLGAEASCQ KGERVLLTQY LGHSSPKCLP PTLHLVCTQF SLYLVDERLP LVPMLKWNHG LPSPLLLARL LPPPRPSCVQ PLLLGGQGGQ LQLLHLAEGA SVPRLAGPPQ SLPSRIDSLP AFPLLEPKIQ WRLQERLKAP TIGLAAVVPP MPSAPTPGLV LFQLSAAGDV FYQQLRPQVD SSLRRDAGPP GDTQPDCHAP TASWTSQDTA GCSQWLKALL KVPLAPPVWT APTFTHRQML GSTELRREEE EGQRLGVLRK AMARGQLLLQ RDLGSLPAAE PPPAPESGLE DKLSERLGEA WAGRGAAWWE RQQGRTSEPG RQTRRPKRRT QLSSSFSLSG HVDPSEDTSS PHSPEWPPAD ALPLPPTTPP SQELTPDACA QGVPSEQRQM LRDYMAKLPP QRDTPGCATT PPHSQASSVR ATRSQQHTPV LSSSQPLRKK PRMGF
Target Information
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RNA polymerase I-specific TBP-associated factor 110 kDa; SL1, 110kD subunit; TAFI110; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein associated factor 1C; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; transcription factor SL1; Transcription initiation factor SL1/TIF-IB subunit C
Gene Aliases: MGC:39976; SL1; TAF1C; TAFI110; TAFI95
UniProt ID: (Human) Q15572
Entrez Gene ID: (Human) 9013
regulation of transcription, DNA-templated
transcription from RNA polymerase I promoter
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
positive regulation of gene expression, epigenetic
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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