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Proteintech
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Immunogen sequence: MKRVRTEQI QMAVSCYLKR RQYVDSDGPL KQGLRLSQTA EEMAANLTVQ SESGCANIVS AAPCQAEPQQ YEVQFGRLRN FLTDSDSQHS HEVMPLLYPL FVYLHLNLVQ NSPKSTVESF YSRFHGMFLQ NASQKDVIEQ LQTTQTIQDI LSNFKLRAFL DNKYVVRLQE DSYNYLIRYL QSDNNTALCK VLTLHIHLDV QPAKRTDYQL YASGSSSRSE NNGLEPPDMP SPILQNEAAL EVLQESIKRV KDGPPSLTTI CFYAFYNTEQ LLNTAEISPD SKLLAAGFDN SCIKLWSLRS KKLKSEPHQV DVSRIHLACD ILEEEV (1-325 aa encoded by B C041094)
TAF5L (TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L), also known as PAF65B, is a 589 amino acid protein that localizes to the nucleus and contains six WD repeats. Existing as a component of the PCAF histone acetylase complex, TAF5L interacts with a number of TAFs and, via this interaction, plays a role in histone acetylation and transcription initiation. Defects in the gene encoding TAF5L, which is expressed as multiple alternatively spliced isoforms, are associated with the pathogenesis of type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PAF65-beta; PCAF associated factor 65 beta; PCAF-associated factor 65 beta; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF5L; TATA box binding protein associated factor 5 like
Gene Aliases: 1110005N04Rik; AI849020; PAF65B; TAF5L
UniProt ID: (Human) O75529, (Mouse) Q91WQ5
Entrez Gene ID: (Human) 27097, (Mouse) 102162, (Rat) 307927
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