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Antibody detects endogenous levels of total TAF6L.
In eukaryotic systems, the process of initiating transcription from protein-coding genes requires the presence of RNA polymerase II and a broad family of auxiliary transcription factors. TFIID is a general transcription factor that initiates preinitiation complex assembly through direct interaction with the TATA promoter element. Functioning as a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs), TFIID mediates promoter responses to various transcriptional activators and repressors. TAF6L, also known as PAF65A, is a 622 amino acid nuclear protein that functions as part of the PCAF (p300/CBP-associated factor) histone acetylase complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: p300/CBP-associated factor (PCAF)-associated factor 65; PAF65-alpha; PCAF-associated factor 65 alpha; PCAF-associated factor 65-alpha; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF6L; TATA box binding protein associated factor 6 like
Gene Aliases: 2810417N14Rik; BB223262; C530024J06Rik; PAF65A; TAF6L
UniProt ID: (Human) Q9Y6J9, (Mouse) Q8R2K4
Entrez Gene ID: (Human) 10629, (Mouse) 225895
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