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FIGURE: 1 / 1
Positive test controls include: 293T, A-431, HL-60, SW480, Mouse brain, Mouse kidney, Rat liver, Rat brain. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN TGEIKALAGC DFLTISPKLL GELLQDNAKL VPVLSAKAAQ ASDLEKIHLD EKSFRWLHNE DQMAVEKLSD GIRKFAADAV KLERMLTERM FNAENGK
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dihydroxyacetone transferase; glycerone transferase; testicular secretory protein Li 56; Transaldolase
Gene Aliases: TAL; TAL-H; TALDO; TALDO1; TALDOR; TALH
UniProt ID: (Human) P37837, (Rat) Q9EQS0, (Mouse) Q93092
Entrez Gene ID: (Human) 6888, (Rat) 83688, (Mouse) 21351
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