Product References
Differential Hsp90-dependent gene expression is strain-specific and common among yeast strains.
iScience
Hung PH,Liao CW,Ko FH,Tsai HK,Leu JY
CAB1001 was used in Western Blot to provide evidence that individual strains can readily display specific Hsp90-dependent gene expression, suggesting that the evolutionary impacts of Hsp90 are widespread in nature.
Fri May 19 00:00:00 UTC 2023
--Atg9 interactions via its transmembrane domains are required for phagophore expansion during autophagy.
Autophagy
Chumpen Ramirez S,Gómez-Sánchez R,Verlhac P,Hardenberg R,Margheritis E,Cosentino K,Reggiori F,Ungermann C
CAB1001 was used in Western Blot to reveal that interactions of Atg9 trimers via their transmembrane segments play a key role in phagophore expansion beyond Atg9's role as a lipid scramblase.
Mon May 01 00:00:00 UTC 2023
Neo-functionalization in Saccharomyces cerevisiae: a novel Nrg1-Rtg3 chimeric transcriptional modulator is essential to maintain mitochondrial DNA integrity.
Royal Society open science
Campero-Basaldua C,González J,García JA,Ramírez E,Hernández H,Aguirre B,Torres-Ramírez N,Márquez D,Sánchez NS,Gómez-Hernández N,Torres-Machorro AL,Riego-Ruiz L,Scazzocchio C,González A
CAB1001 was used in Western Blot to show a novel function of these two proteins, in which alanine promotes the formation of a chimeric Nrg1/Rtg3 regulator that represses the ALT2 gene (encoding an alanine transaminase paralog of unknown function).
Wed Nov 01 00:00:00 UTC 2023
Perturbed fatty-acid metabolism is linked to localized chromatin hyperacetylation, increased stress-response gene expression and resistance to oxidative stress.
PLoS genetics
Princová J,Salat-Canela C,Daněk P,Marešová A,de Cubas L,Bähler J,Ayté J,Hidalgo E,Převorovský M
CAB1001 was used in Western Blotting to propose that changes in lipid metabolism can regulate the chromatin and transcription of specific stress-response genes, which in turn might help cells to maintain redox homeostasis.
Sun Jan 01 00:00:00 UTC 2023
A distinct P-body-like granule is induced in response to the disruption of microtubule integrity in Saccharomyces cerevisiae.
Genetics
Hurst Z,Liu W,Shi Q,Herman PK
CAB1001 was used in Immunoprecipitation to suggest that the disruption of microtubule integrity leads to the formation of a novel type of Processing-body granule that may have distinct biological activities in the cell.
Tue Aug 30 00:00:00 UTC 2022
The Zip4 protein directly couples meiotic crossover formation to synaptonemal complex assembly.
Genes & development
Pyatnitskaya A,Andreani J,Guérois R,De Muyt A,Borde V
CAB1001 was used in Western Blotting to show that Ecm11, a SC central element protein, localizes on both DSB sites and sites that attach chromatin loops to the chromosome axis, which are the starting points of SC formation, in a way that strictly requires the ZMM protein Zip4.
Sat Jan 01 00:00:00 UTC 2022
Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory.
eLife
Sump B,Brickner DG,D'Urso A,Kim SH,Brickner JH
CAB1001 was used in ChIP assay to provide a compelling example of a heritable histone modification that stimulates future transcription and is inherited over a shorter timescale than other heritable histone modifications like H3K9 or H3K27 methylation.
Tue May 17 00:00:00 UTC 2022
Impairment of transcription factor Gcr1p binding motif perturbs OPI3 transcription in Saccharomyces cerevisiae.
Journal of cellular biochemistry
Chidambaram R,Ramachandran G,Rajasekharan R,Nachiappan V
CAB1001 was used in Western Blot to study the role of the GCR1 transcription factor in lipid metabolism in Saccharomyces cerevisiae and uncover GCR1 regulation of OPI3 expression.
Wed Jun 01 00:00:00 UTC 2022
A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition.
Mobile DNA
Barkova A,Adhya I,Conesa C,Asif-Laidin A,Bonnet A,Rabut E,Chagneau C,Lesage P,Acker J
CAB1001 was used in Western Blotting to show that Ty1 IN is phosphorylated, as observed for retroviral INs, highlighting an important role of CK2 in the regulation of Ty1 retrotransposition.
Fri Nov 18 00:00:00 UTC 2022
Enzymatic transfer of acetate on histones from lysine reservoir sites to lysine activating sites.
Science advances
Mendoza M,Egervari G,Sidoli S,Donahue G,Alexander DC,Sen P,Garcia BA,Berger SL
CAB1001 was used in ChIP assay to test a hypothesis that during gene activation, a local transfer of intact acetate occurs via sequential action of epigenetic and metabolic enzymes.
Fri Jan 21 00:00:00 UTC 2022
The RNA-bound proteome of MRSA reveals post-transcriptional roles for helix-turn-helix DNA-binding and Rossmann-fold proteins.
Nature communications
Chu LC,Arede P,Li W,Urdaneta EC,Ivanova I,McKellar SW,Wills JC,Fröhlich T,von Kriegsheim A,Beckmann BM,Granneman S
CAB1001 was used in Western Blotting to identify hundreds of putative RNA-binding proteins, many containing unconventional RNA-binding domains such as Rossmann-fold domains.
Tue May 24 00:00:00 UTC 2022
Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex.
Nature communications
Foucher AE,Touat-Todeschini L,Juarez-Martinez AB,Rakitch A,Laroussi H,Karczewski C,Acajjaoui S,Soler-López M,Cusack S,Mackereth CD,Verdel A,Kadlec J
CAB1001 was used in Immunocytochemistry-immunoflourescence to eliminate specific or aberrant transcripts, eukaryotes use nuclear RNA-targeting complexes that deliver them to the exosome for degradation.
Wed Aug 24 00:00:00 UTC 2022
The yeast LYST homolog Bph1 is a Rab5 effector and prevents Atg8 lipidation at endosomes.
Journal of cell science
Vargas Duarte P,Hardenberg R,Mari M,Walter S,Reggiori F,Fröhlich F,González Montoro A,Ungermann C
CAB1001 was used in Western Blotting to suggest that Bph1 is a novel Rab5 effector that maintains endosomal functioning.
Fri Apr 15 00:00:00 UTC 2022
Cold-induced Arabidopsis FRIGIDA nuclear condensates for FLC repression.
Nature
Zhu P,Lister C,Dean C
CAB1001 was used in Western Blot to show that cold rapidly promotes the formation of FRI nuclear condensates that do not colocalize with an active FLC locus.
Mon Nov 01 00:00:00 UTC 2021
The Pif1 helicase is actively inhibited during meiotic recombination which restrains gene conversion tract length.
Nucleic acids research
Vernekar DV,Reginato G,Adam C,Ranjha L,Dingli F,Marsolier MC,Loew D,Guérois R,Llorente B,Cejka P,Borde V
CAB1001 was used in Western Blotting to show that Pif1, through its interaction with PCNA, is required for the long gene conversions observed in the absence of MutLβ recruitment to recombination sites.
Fri May 07 00:00:00 UTC 2021
Heh2/Man1 may be an evolutionarily conserved sensor of NPC assembly state.
Molecular biology of the cell
Borah S,Thaller DJ,Hakhverdyan Z,Rodriguez EC,Isenhour AW,Rout MP,King MC,Lusk CP
CAB1001 was used in Western Blot to propose a model in which Heh2 acts as a sensor of NPC assembly state, which may be important for NPC quality control mechanisms and the segregation of NPCs during cell division.
Thu Jul 15 00:00:00 UTC 2021
Protein phosphatase 1 in association with Bud14 inhibits mitotic exit in Saccharomyces cerevisiae.
eLife
Kocakaplan D,Karabürk H,Dilege C,Kirdök I,Bektas SN,Caydasi AK
CAB1001 was used in Western Blot to identify proteins involved in spindle position checkpoint.
Mon Oct 11 00:00:00 UTC 2021
Regulation of the MLH1-MLH3 endonuclease in meiosis.
Nature
Cannavo E,Sanchez A,Anand R,Ranjha L,Hugener J,Adam C,Acharya A,Weyland N,Aran-Guiu X,Charbonnier JB,Hoffmann ER,Borde V,Matos J,Cejka P
CAB1001 was used in Western Blotting to biochemically reconstitute key elements of the MLH1-MLH3 (MutLγ) nuclease dependent pro-crossover pathway which facilitates proper chromosome segregation and enables the reciprocal exchange of DNA segments between homologous chromosomes.
Thu Oct 01 00:00:00 UTC 2020
Differential Scaling of Gene Expression with Cell Size May Explain Size Control in Budding Yeast.
Molecular cell
Chen Y,Zhao G,Zahumensky J,Honey S,Futcher B
CAB1001 was used in Immunocytochemistry to provide evidence to suggest that size homeostasis comes from differential scaling of gene expression with size. Differential regulation of gene expression as a function of cell size could affect many cellular processes.
Thu Apr 16 00:00:00 UTC 2020
Nascent Transcript Folding Plays a Major Role in Determining RNA Polymerase Elongation Rates.
Molecular cell
Turowski TW,Petfalski E,Goddard BD,French SL,Helwak A,Tollervey D
CAB1001 was used in Chromatin immunoprecipitation to investigate the sequence specific regulation during RNA processing in S cerevisiae.
Thu Aug 06 00:00:00 UTC 2020
Mechanism of Long-Range Chromosome Motion Triggered by Gene Activation.
Developmental cell
Wang A,Kolhe JA,Gioacchini N,Baade I,Brieher WM,Peterson CL,Freeman BC
CAB1001 was used in Western Blotting to delineate a molecular chaperone-dependent pathway for relocating activated gene loci in yeast.
Mon Feb 10 00:00:00 UTC 2020
Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase.
The Journal of cell biology
Wang Y,Yuan P,Grabon A,Tripathi A,Lee D,Rodriguez M,Lönnfors M,Eisenberg-Bord M,Wang Z,Man Lam S,Schuldiner M,Bankaitis VA
CAB1001 was used in Western Blot, Immunoprecipitation to show Sec14-like protein and a lipid kinase regulate phosphatidylserine metabolism.
Mon May 04 00:00:00 UTC 2020
Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase.
The Journal of cell biology
Wang Y,Yuan P,Grabon A,Tripathi A,Lee D,Rodriguez M,Lönnfors M,Eisenberg-Bord M,Wang Z,Man Lam S,Schuldiner M,Bankaitis VA
CAB1001 was used in Western Blot, Immunoprecipitation to show Sec14-like protein and a lipid kinase regulate phosphatidylserine metabolism.
Mon May 04 00:00:00 UTC 2020
Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags.
Journal of proteome research
Storey AJ,Hardman RE,Byrum SD,Mackintosh SG,Edmondson RD,Wahls WP,Tackett AJ,Lewis JA
CAB1001 was used in Western Blotting to show tandem mass tagging and triple-stage mass spectrometry enables peptide-level quantification of samples.
Fri Mar 06 00:00:00 UTC 2020
Cdc48 regulates intranuclear quality control sequestration of the Hsh155 splicing factor in budding yeast.
Journal of cell science
Mathew V,Kumar A,Jiang YK,West K,Tam AS,Stirling PC
CAB1001 was used in Immunoprecipitation to demonstrate the role of Cdc48 in the regulation or stabilization of splicing subcomplexes.
Thu Dec 03 00:00:00 UTC 2020
Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover.
Molecular and cellular biology
Liu G,Byrd A,Warner AN,Pei F,Basha E,Buchanan A,Buchan JR
CAB1001 was used in Western Blotting to discover a role for Cdc48/VCP in regulating the toxicity and turnover of TDP-43 and FUS in amyotrophic lateral sclerosis.
Thu Jan 30 00:00:00 UTC 2020
Active transcription and Orc1 drive chromatin association of the AAA+ ATPase Pch2 during meiotic G2/prophase.
PLoS genetics
Cardoso da Silva R,Villar-Fernández MA,Vader G
CAB1001 was used in Western Blotting to describe a comprehensive mapping of Pch2 localization across the budding yeast genome during meiotic G2/prophase.
Mon Jun 01 00:00:00 UTC 2020
A conserved and regulated mechanism drives endosomal Rab transition.
eLife
Langemeyer L,Borchers AC,Herrmann E,Füllbrunn N,Han Y,Perz A,Auffarth K,Kümmel D,Ungermann C
CAB1001 was used in Western Blotting to uncover the minimal feed-forward machinery of the endosomal Rab cascade and a novel regulatory mechanism controlling this pathway.
Mon May 11 00:00:00 UTC 2020
Inhibition of post-termination ribosome recycling at premature termination codons in UPF1 ATPase mutants.
eLife
Serdar LD,Whiteside DL,Nock SL,McGrath D,Baker KE
CAB1001 was used in Immunoprecipitation to reveal a failure in post-termination ribosome recycling in UPF1 ATPase mutants.
Wed Jul 22 00:00:00 UTC 2020
The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae.
PLoS genetics
Alme EB,Stevenson E,Krogan NJ,Swaney DL,Toczyski DP
CAB1001 was used in Western Blotting to show that Isr1 acts as a negative regulator of the highly-conserved hexosamine biosynthesis pathway (HBP), which converts glucose into uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), the carbohydrate precursor to protein glycosylation, GPI-anchor formation, and chitin biosynthesis.
Mon Jun 01 00:00:00 UTC 2020
The Transcription Factor Stp2 Is Important for Candida albicans Biofilm Establishment and Sustainability.
Frontiers in microbiology
Böttcher B,Hoffmann B,Garbe E,Weise T,Cseresnyés Z,Brandt P,Dietrich S,Driesch D,Figge MT,Vylkova S
CAB1001 was used in Western Blotting to show the transcription factor Stp2 is important for C. albicans biofilm formation, where it contributes to adherence and induction of morphogenesis, and mediates nutrient adaption and cell longevity in mature biofilms.
Mon Sep 28 00:00:00 UTC 2020
GCN sensitive protein translation in yeast.
PloS one
Barr WA,Sheth RB,Kwon J,Cho J,Glickman JW,Hart F,Chatterji OK,Scopino K,Voelkel-Meiman K,Krizanc D,Thayer KM,Weir MP
CAB1001 was used in Western Blotting to suggest a model in which the C1054-A1196-R146 (CAR) interaction surface can act as both an accelerator and braking system for ribosome translation.
Mon Oct 26 00:00:00 UTC 2020
Mps2 links Csm4 and Mps3 to form a telomere-associated LINC complex in budding yeast.
Life science alliance
Fan J,Jin H,Koch BA,Yu HG
CAB1001 was used in Western Blotting to study the interaction between KASH-like proteins Csm4 and Mps3 and the influence of SUN domain protein Mps3 on this pair.
Tue Dec 01 00:00:00 UTC 2020
Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation.
Nature communications
Chen G,Wang D,Wu B,Yan F,Xue H,Wang Q,Quan S,Chen Y
CAB1001 was used in Immunoprecipitation to demonstrate that the extra-terminal (ET) domain of Taf14 (Taf14ET) recognizes a common motif in multiple transcriptional coactivator proteins from several nuclear complexes, including RSC, SWI/SNF, INO80, NuA3, TFIID, and TFIIF.
Fri Aug 21 00:00:00 UTC 2020
Induction of triacylglycerol synthesis in yeast by cell cycle arrest.
FEMS yeast research
Madeira JB,Matos GS,Messias LS,Bozaquel-Morais BL,Masuda CA,Montero-Lomeli M
CAB1001 was used in Western Blotting to highlight the tole of the cell cycle regulator SWI4 in the coordination of lipid metabolism which is independent of the TORC1 and SNF1/AMPK pathways.
Wed May 01 00:00:00 UTC 2019
Auxin-Inducible Depletion of the Essentialome Suggests Inhibition of TORC1 by Auxins and Inhibition of Vrg4 by SDZ 90-215, a Natural Antifungal Cyclopeptide.
G3 (Bethesda, Md.)
Snyder NA,Kim A,Kester L,Gale AN,Studer C,Hoepfner D,Roggo S,Helliwell SB,Cunningham KW
CAB1001 was used in Western Blotting to show that AID-tagging can efficiently model the action of small molecule inhibitors (SMI) before they are discovered and can facilitate SMI discovery.
Thu Mar 07 00:00:00 UTC 2019
A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe.
BMC genomics
Vassiliadis D,Wong KH,Andrianopoulos A,Monahan BJ
CAB1001 was used in Immunohistochemistry to define the gene regulatory networks of carbon catabolite repression in fission yeast and revealed the transcriptional complexities governing this system.
Fri Mar 29 00:00:00 UTC 2019
Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo.
Nucleic acids research
Sen ND,Gupta N,K Archer S,Preiss T,Lorsch JR,Hinnebusch AG
CAB1001 was used in Western Blot to reveal that the translational efficiencies of many more mRNAs are reduced in a ded1-ts dbp1Δ double mutant versus either single mutant, becoming highly dependent on Dbp1 or Ded1 only when the other helicase is impaired.
Thu Sep 19 00:00:00 UTC 2019
Molecular interactions between Hel2 and RNA supporting ribosome-associated quality control.
Nature communications
Winz ML,Peil L,Turowski TW,Rappsilber J,Tollervey D
CAB1001 was used in Western Blotting to demonstrate a ribosome-associated quality control molecular mechanism, in which Hel2 associates with ribosomal subunits and scans ribosome-mRNA complexes.
Mon Feb 04 00:00:00 UTC 2019
Puf6 and Loc1 Are the Dedicated Chaperones of Ribosomal Protein Rpl43 in Saccharomyces cerevisiae.
International journal of molecular sciences
Liang KJ,Yueh LY,Hsu NH,Lai JS,Lo KY
CAB1001 was used in Western Blot to find that Puf6 and Loc1 are the dedicated chaperones of ribosomal protein Rpl43 and also analyzed the potential interaction domains among the three proteins.
Tue Nov 26 00:00:00 UTC 2019
Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin-ligand-type complexes.
Nature communications
Ahmed YL,Thoms M,Mitterer V,Sinning I,Hurt E
CAB1001 was used in Western Blotting to show the versatility of the MIDAS fold for mechanical force transmission in processes as varied as integrin-mediated cell adhesion and mechanochemical removal of assembly factors from pre-ribosomes.
Thu Jul 11 00:00:00 UTC 2019
Functional divergence of a global regulatory complex governing fungal filamentation.
PLoS genetics
Polvi EJ,Veri AO,Liu Z,Hossain S,Hyde S,Kim SH,Tebbji F,Sellam A,Todd RT,Xie JL,Lin ZY,Wong CJ,Shapiro RS,Whiteway M,Robbins N,Gingras AC,Selmecki A,Cowen LE
CAB1001 was used in Western Blotting to highlight rewiring of key morphogenetic regulators over evolutionary time and aneuploidy as an adaptive mechanism driving fungal morphogenesis.
Tue Jan 01 00:00:00 UTC 2019
Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.
Nature
Verma R,Reichermeier KM,Burroughs AM,Oania RS,Reitsma JM,Aravind L,Deshaies RJ
CAB1001 was used in Western Blotting to determine the role of the Cdc48 adaptor Vms1 in stalled ribosomes.
Tue May 01 00:00:00 UTC 2018
Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.
Nucleic acids research
van Welsem T,Korthout T,Ekkebus R,Morais D,Molenaar TM,van Harten K,Poramba-Liyanage DW,Sun SM,Lenstra TL,Srivas R,Ideker T,Holstege FCP,van Attikum H,El Oualid F,Ovaa H,Stulemeijer IJE,Vlaming H,van Leeuwen F
CAB1001 was used in Western Blotting to show that Dot1 and H2Bub1 are subject to bi-directional crosstalk and that Dot1 possesses chromatin regulatory functions that are independent of its methyltransferase activity.
Fri Nov 30 00:00:00 UTC 2018
Heterologous Hsp90 promotes phenotypic diversity through network evolution.
PLoS biology
Koubkova-Yu TC,Chao JC,Leu JY
CAB1001 was used in Western Blotting to show that cells adapt to a heterologous Hsp90 by modifying different subnetworks, facilitating the evolution of phenotypic diversity inaccessible to wild-type cells.
Thu Nov 01 00:00:00 UTC 2018
Molecular signature of the imprintosome complex at the mating-type locus in fission yeast.
Microbial cell (Graz, Austria)
Raimondi C,Jagla B,Proux C,Waxin H,Gangloff S,Arcangioli B
CAB1001 was used in Chromatin immunoprecipitation to characterize the recruitment of early players of mating type switching at the mat1 region.
Tue Jan 16 00:00:00 UTC 2018
A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A.
Genetics
Ciftci-Yilmaz S,Au WC,Mishra PK,Eisenstatt JR,Chang J,Dawson AR,Zhu I,Rahman M,Bilke S,Costanzo M,Baryshnikova A,Myers CL,Meltzer PS,Landsman D,Baker RE,Boone C,Basrai MA
CAB1001 was used in Western blotting to define a novel role for the HIR complex in preventing mislocalization of Cse4 by facilitating proteolysis of Cse4, thereby promoting genome stability.
Sat Sep 01 00:00:00 UTC 2018
A balance of deubiquitinating enzymes controls cell cycle entry.
Molecular biology of the cell
Mapa CE,Arsenault HE,Conti MM,Poti KE,Benanti JA
CAB1001 was used in Western Blotting to study the role of deubiquitinating enzymes in Protein degradation during the cell cycle.
Thu Nov 15 00:00:00 UTC 2018
The half-bridge component Kar1 promotes centrosome separation and duplication during budding yeast meiosis.
Molecular biology of the cell
Agarwal M,Jin H,McClain M,Fan J,Koch BA,Jaspersen SL,Yu HG
CAB1001 was used in Western Blotting to show that an overproduction of half-bridge component Kar1 leads to premature spindle pole body separation during meiosis.
Wed Aug 01 00:00:00 UTC 2018
A guanine nucleotide exchange factor (GEF) limits Rab GTPase-driven membrane fusion.
The Journal of biological chemistry
Langemeyer L,Perz A,Kümmel D,Ungermann C
CAB1001 was used in Western Blotting to reveal that GEF Mon1-Ccz1 is necessary and sufficient for stabilizing prenylated Ypt7 on membranes and conclude that GEF can control the entire fusion cascade.
Fri Jan 12 00:00:00 UTC 2018
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space.
PLoS genetics
Veri AO,Miao Z,Shapiro RS,Tebbji F,O'Meara TR,Kim SH,Colazo J,Tan K,Vyas VK,Whiteway M,Robbins N,Wong KH,Cowen LE
CAB1001 was used in Western Blotting to establish an intriguing paradigm whereby overexpression or depletion of Candida albicans HSF1 induces morphogenesis in the absence of external cues.
Thu Mar 01 00:00:00 UTC 2018
N-terminal Acetylation Levels Are Maintained During Acetyl-CoA Deficiency in Saccharomyces cerevisiae.
Molecular & cellular proteomics : MCP
Varland S,Aksnes H,Kryuchkov F,Impens F,Van Haver D,Jonckheere V,Ziegler M,Gevaert K,Van Damme P,Arnesen T
CAB1001 was used in Western Blotting to demonstrate, using a Saccharomyces cerevisiae model, the resilience of N-terminal acetylation to changes in cellular metabolism.
Sat Dec 01 00:00:00 UTC 2018
Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison.
PloS one
Schuyler SC,Wu YO,Chen HY,Ding YS,Lin CJ,Chu YT,Chen TC,Liao L,Tsai WW,Huang A,Wang LI,Liao TW,Jhuo JH,Cheng V
CAB1001 was used in Western Blotting to hypothesize that Cdc20 Mad2-binding motif peptides, Tyc1 and human hp31 peptide can serve as novel molecular tools for investigating APC/C inhibition that leads to sensitivity to microtubule poison in vivo.
Fri Jan 11 00:00:00 UTC 2019
Impaired cohesion and homologous recombination during replicative aging in budding yeast.
Science advances
Pal S,Postnikoff SD,Chavez M,Tyler JK
CAB1001 was used in western blotting to confirm the levels of TAP-tagged proteins.
Thu Feb 01 00:00:00 UTC 2018
General decapping activators target different subsets of inefficiently translated mRNAs.
eLife
He F,Celik A,Wu C,Jacobson A
CAB1001 was used in Western Blotting to determine the roles of Pat1, Lsm1, and Dhh1 in decapping of general mRNAs.
Thu Dec 06 00:00:00 UTC 2018
The ATPase Fap7 Tests the Ability to Carry Out Translocation-like Conformational Changes and Releases Dim1 during 40S Ribosome Maturation.
Molecular cell
Ghalei H,Trepreau J,Collins JC,Bhaskaran H,Strunk BS,Karbstein K
CAB1001 was used in Western Blotting to show that the essential ATPase Fap7 promotes formation of the rotated state thereby releasing the essential assembly factor Dim1 from pre-40S subunits.
Thu Sep 21 00:00:00 UTC 2017
Rps26 directs mRNA-specific translation by recognition of Kozak sequence elements.
Nature structural & molecular biology
Ferretti MB,Ghalei H,Ward EA,Potts EL,Karbstein K
CAB1001 was used in Western Blotting to reveal that Rps26 contributes to mRNA-specific translation by recognition of the Kozak sequence in well-translated mRNAs and that Rps26-deficient ribosomes preferentially translate mRNA from select stress-response pathways.
Fri Sep 01 00:00:00 UTC 2017
Mitochondrial-nuclear co-evolution leads to hybrid incompatibility through pentatricopeptide repeat proteins.
EMBO reports
Jhuang HY,Lee HY,Leu JY
CAB1001 was used in western blot to explore the contribution of Ccm1 and 15S rRNA to the hybrid incompatibility of two yeast species
Sun Jan 01 00:00:00 UTC 2017
Yeast phospholipase C is required for stability of casein kinase I Yck2p and expression of hexose transporters.
FEMS microbiology letters
Zhang T,Galdieri L,Hasek J,Vancura A
CAB1001 was used in Western Blotting to propose a model in which plc1 mutation causes increased internalization of glucose transporters, decreased transport of glucose into the cells, and consequently decreased stability of Yck1/2p, increased stability of Mth1p and decreased expression of the HXT genes.
Fri Dec 01 00:00:00 UTC 2017
The dynamic three-dimensional organization of the diploid yeast genome.
eLife
Kim S,Liachko I,Brickner DG,Cook K,Noble WS,Brickner JH,Shendure J,Dunham MJ
CAB1001 was used in Chromatin immunoprecipitation to study how homolog pairing in diploids or environmental conditions influence overall genome organisation.
Wed May 24 00:00:00 UTC 2017
Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization.
Molecular cell
Rodríguez-Molina JB,Tseng SC,Simonett SP,Taunton J,Ansari AZ
CAB1001 was used in ChIP assay to determine the role of Kin28 in transcription in vivo
Thu Aug 04 00:00:00 UTC 2016
Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling.
Nature structural & molecular biology
Barrio-Garcia C,Thoms M,Flemming D,Kater L,Berninghausen O,Baßler J,Beckmann R,Hurt E
CAB1001 was used in western blot to report the cryo-EM structure of a Saccharomyces cerevisiae nucleoplasmic pre-60S particle containing the dynein-related 550-kDa Rea1 AAA(+) ATPase and the Rix1 subcomplex
Fri Jan 01 00:00:00 UTC 2016
Decoupling of divergent gene regulation by sequence-specific DNA binding factors.
Nucleic acids research
Yan C,Zhang D,Raygoza Garay JA,Mwangi MM,Bai L
CAB1001 was used in ChIP assay to elucidate the mechanism underlying differential gene pair regulation.
Thu Sep 03 00:00:00 UTC 2015
Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing.
Proceedings of the National Academy of Sciences of the United States of America
Chalamcharla VR,Folco HD,Dhakshnamoorthy J,Grewal SI
CAB1001 was used in immunoprecipitation and western blot to study factors that regulate heterochromatin assembly
Tue Dec 22 00:00:00 UTC 2015
Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination.
Molecular biology of the cell
Mishra PK,Guo J,Dittman LE,Haase J,Yeh E,Bloom K,Basrai MA
CAB1001 was used in immunoprecipitation to report that Pat1 regulates the structure of CEN chromatin by preventing ubiquitination of Cse4.
Mon Jun 01 00:00:00 UTC 2015
An in vivo detection system for transient and low-abundant protein interactions and their kinetics in budding yeast.
Yeast (Chichester, England)
Brezovich A,Schuschnig M,Ammerer G,Kraft C
CAB1001 was used in western blot to describe inducible systems to study very low-abundant proteins at their native expression levels, two prey proteins expressed in a single cell, and the effects of inducible methylation in these systems
Sun Mar 01 00:00:00 UTC 2015
Activation of the mitochondrial signaling pathway in response to organic solvent stress in yeast.
Current genetics
Nishida-Aoki N,Mori H,Kuroda K,Ueda M
CAB1001 was used in ChIP assay and western blot to study the roles of Pdr1p and Pdr3p to organic solvent stress
Fri May 01 00:00:00 UTC 2015
Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States.
PloS one
Diezmann S,Leach MD,Cowen LE
CAB1001 was used in western blot to examine proteins that interact with Hsp90 to regulate biofilm formation
Thu May 19 00:00:00 UTC 2016
Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles.
PloS one
Převorovský M,Oravcová M,Tvarůžková J,Zach R,Folk P,Půta F,Bähler J
CAB1001 was used in western blot to study Cbf11 and Cbf12 during cell-cycle progression
Mon Jun 06 00:00:00 UTC 2016
14-3-3ζ coordinates adipogenesis of visceral fat.
Nature communications
Lim GE,Albrecht T,Piske M,Sarai K,Lee JTC,Ramshaw HS,Sinha S,Guthridge MA,Acker-Palmer A,Lopez AF,Clee SM,Nislow C,Johnson JD
CAB1001 was used in western blot to determine the role of 14-3-3zeta in adipogenesis
Wed Jul 29 00:00:00 UTC 2015
DNA Damage Response Checkpoint Activation Drives KP1019 Dependent Pre-Anaphase Cell Cycle Delay in S. cerevisiae.
PloS one
Bierle LA,Reich KL,Taylor BE,Blatt EB,Middleton SM,Burke SD,Stultz LK,Hanson PK,Partridge JF,Miller ME
CAB1001 was used in western blot to investigate the role of KP1019 in the DNA damage response
Fri May 27 00:00:00 UTC 2016
Hbr1 Activates and Represses Hyphal Growth in Candida albicans and Regulates Fungal Morphogenesis under Embedded Conditions.
PloS one
Pendrak ML,Roberts DD
CAB1001 was used in western blot to describe a role for Hbr1 in hyphal development
Mon Feb 22 00:00:00 UTC 2016
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition.
PLoS genetics
Moldovan JB,Moran JV
CAB1001 was used in western blot to elucidate how ZAP regulates the retrotransposition of LINE and Alu elements.
Fri May 01 00:00:00 UTC 2015
RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nature communications
Wilinski D,Qiu C,Lapointe CP,Nevil M,Campbell ZT,Tanaka Hall TM,Wickens M
CAB1001 was used in western blot to report the mRNA targets of S. cerevisiae PUF5p
Mon Sep 14 00:00:00 UTC 2015
Hst3 is turned over by a replication stress-responsive SCF(Cdc4) phospho-degron.
Proceedings of the National Academy of Sciences of the United States of America
Edenberg ER,Vashisht AA,Topacio BR,Wohlschlegel JA,Toczyski DP
CAB1001 was used in western blot to study the mechanisms involved in the turnover of the Hst3 histone deacetylase protein
Tue Apr 22 00:00:00 UTC 2014
A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.
PLoS biology
Lahiri S,Chao JT,Tavassoli S,Wong AK,Choudhary V,Young BP,Loewen CJ,Prinz WA
CAB1001 was used in Western Blot to show that the ER membrane protein complex tethers ER to mitochonfria which is required for phospholipid synthesis and cell growth.
Wed Oct 01 00:00:00 UTC 2014
Molecular mechanisms of selective estrogen receptor modulator activity in human breast cancer cells: identification of novel nuclear cofactors of antiestrogen-ERα complexes by interaction proteomics.
Journal of proteome research
Cirillo F,Nassa G,Tarallo R,Stellato C,De Filippo MR,Ambrosino C,Baumann M,Nyman TA,Weisz A
CAB1001 was used in western blot to identify novel cofactors of estrogen receptor-alpha/anti-estrogen complexes using an interaction proteomics approach in hormone-responsive breast cancer cells
Fri Jan 04 00:00:00 UTC 2013
A systematic approach for the genetic dissection of protein complexes in living cells.
Cell reports
Diss G,Dubé AK,Boutin J,Gagnon-Arsenault I,Landry CR
CAB1001 was used in western blot to develop a systematic approach for studying protein complexes in living cells
Thu Jun 27 00:00:00 UTC 2013
Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel.
Nature structural & molecular biology
Bradatsch B,Leidig C,Granneman S,Gnädig M,Tollervey D,Böttcher B,Beckmann R,Hurt E
CAB1001 was used in western blot to study the structure of the pre-60S ribosomal subunit with bound Arx1 using electron microscopy
Sat Dec 01 00:00:00 UTC 2012
Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.
The EMBO journal
Kraft C,Kijanska M,Kalie E,Siergiejuk E,Lee SS,Semplicio G,Stoffel I,Brezovich A,Verma M,Hansmann I,Ammerer G,Hofmann K,Tooze S,Peter M
CAB1001 was used in immunoprecipitation to examine the role of the interaction between Atg1/ULK1 kinase and Atg8 in autophagy
Wed Sep 12 00:00:00 UTC 2012
Direct regulation of microRNA biogenesis and expression by estrogen receptor beta in hormone-responsive breast cancer.
Oncogene
Paris O,Ferraro L,Grober OM,Ravo M,De Filippo MR,Giurato G,Nassa G,Tarallo R,Cantarella C,Rizzo F,Di Benedetto A,Mottolese M,Benes V,Ambrosino C,Nola E,Weisz A
CAB1001 was used in western blot to study the role of estrogen receptor-beta in regulating miRNAs in hormone-sensitive breast cancer
Thu Sep 20 00:00:00 UTC 2012
MUC1 drives c-Met-dependent migration and scattering.
Molecular cancer research : MCR
Horm TM,Bitler BG,Broka DM,Louderbough JM,Schroeder JA
CAB1001 was used in western blot to study the role of c-Met in metastatic progression driven by the transmembrane mucin MUC1
Sat Dec 01 00:00:00 UTC 2012
Plo1 phosphorylates Dam1 to promote chromosome bi-orientation in fission yeast.
Journal of cell science
Buttrick GJ,Lancaster TC,Meadows JC,Millar JB
CAB1001 was used in western blot to study the mechanisms underlying chromosome bi-orientation in fission yeast
Sun Apr 01 00:00:00 UTC 2012
Iron-induced dissociation of the Aft1p transcriptional regulator from target gene promoters is an initial event in iron-dependent gene suppression.
Molecular and cellular biology
Ueta R,Fujiwara N,Iwai K,Yamaguchi-Iwai Y
CAB1001 was used in western blot to study the mechanisms of iron-dependent gene suppression
Sat Dec 01 00:00:00 UTC 2012
Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans.
Molecular biology of the cell
Senn H,Shapiro RS,Cowen LE
CAB1001 was used in western blot to investigate the links between Hsp90, morphogenesis and cell cycle progression in Candida albicans
Sun Jan 01 00:00:00 UTC 2012
Osh6 overexpression extends the lifespan of yeast by increasing vacuole fusion.
Cell cycle (Georgetown, Tex.)
Gebre S,Connor R,Xia Y,Jawed S,Bush JM,Bard M,Elsalloukh H,Tang F
CAB1001 was used in western blot to explore whether vacuole fusion extends lifespan of yeast
Fri Jun 01 00:00:00 UTC 2012
Saccharomyces cerevisiae NineTeen complex (NTC)-associated factor Bud31/Ycr063w assembles on precatalytic spliceosomes and improves first and second step pre-mRNA splicing efficiency.
The Journal of biological chemistry
Saha D,Khandelia P,O'Keefe RT,Vijayraghavan U
CAB1001 was used in western blot to characterize the functions and spliceosome interactions of Bud31
Fri Feb 17 00:00:00 UTC 2012
A quantitative, high-throughput reverse genetic screen reveals novel connections between Pre-mRNA splicing and 5' and 3' end transcript determinants.
PLoS genetics
Albulescu LO,Sabet N,Gudipati M,Stepankiw N,Bergman ZJ,Huffaker TC,Pleiss JA
CAB1001 was used in ChIP assay to study connections between Pre-mRNA splicing and 5' and 3' end transcript determinants using a reverse genetic screen
Tue Sep 04 00:00:00 UTC 2012
Interactions of Sen1, Nrd1, and Nab3 with multiple phosphorylated forms of the Rpb1 C-terminal domain in Saccharomyces cerevisiae.
Eukaryotic cell
Chinchilla K,Rodriguez-Molina JB,Ursic D,Finkel JS,Ansari AZ,Culbertson MR
CAB1001 was used in western blot to study interactions between Rpb1 and termination factors in Saccharomyces cerevisiae
Sun Apr 01 00:00:00 UTC 2012
Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1.
Proceedings of the National Academy of Sciences of the United States of America
Moriel-Carretero M,Tous C,Aguilera A
CAB1001 was used in western blot to study the control of TFIIH by the cochaperone Ydj1
Tue Sep 13 00:00:00 UTC 2011
The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1.
The Journal of cell biology
Kurischko C,Kim HK,Kuravi VK,Pratzka J,Luca FC
CAB1001 was used in western blot to determine how the yeast Cbk1 kinase regulates mRNA localization
Mon Feb 21 00:00:00 UTC 2011
Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background.
Development (Cambridge, England)
Cook MS,Munger SC,Nadeau JH,Capel B
CAB1001 was used in western blot to study the impact of genetic background on regulation of male germ cells by DND1
Sat Jan 01 00:00:00 UTC 2011
Insights into the structure of the CCR4-NOT complex by electron microscopy.
FEBS letters
Nasertorabi F,Batisse C,Diepholz M,Suck D,Böttcher B
CAB1001 was used in western blot to explore the CCR4-NOT complex with electron microscopy
Thu Jul 21 00:00:00 UTC 2011
Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning.
Molecular biology of the cell
Stuchell-Brereton MD,Siglin A,Li J,Moore JK,Ahmed S,Williams JC,Cooper JA
CAB1001 was used in western blot to study the role of the interaction between dynein light chain and intermediate chain in mitotic spindle positioning
Mon Aug 01 00:00:00 UTC 2011
Hap2-3-5-Gln3 determine transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions in the yeast Saccharomyces cerevisiae.
Microbiology (Reading, England)
Hernández H,Aranda C,López G,Riego L,González A
CAB1001 was used in western blot to evaluate an artificial transcriptional regulator Hap2-3-5-Gln3 for the study of transcriptional response
Tue Mar 01 00:00:00 UTC 2011
Multiple means to the same end: the genetic basis of acquired stress resistance in yeast.
PLoS genetics
Berry DB,Guan Q,Hose J,Haroon S,Gebbia M,Heisler LE,Nislow C,Giaever G,Gasch AP
CAB1001 was used in western blot to investigate the mechanism for the acquired stress resistance in yeast
Tue Nov 01 00:00:00 UTC 2011
Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.
Journal of translational medicine
Horibe T,Kohno M,Haramoto M,Ohara K,Kawakami K
CAB1001 was used in western blot to investigate the effectiveness of Antp-TPR peptide in anticancer therapy
Fri Jan 14 00:00:00 UTC 2011
Affinity capture of TAP-tagged protein complexes: affinity purification step 2.
Cold Spring Harbor protocols
Link AJ,Weaver C,Farley A
CAB1001 was used in western blot to optimise affinity capture of TAP-tagged protein complexes
Fri Apr 01 00:00:00 UTC 2011
Adjacent gene pairing plays a role in the coordinated expression of ribosome biogenesis genes MPP10 and YJR003C in Saccharomyces cerevisiae.
Eukaryotic cell
Arnone JT,McAlear MA
CAB1001 was used in ChIP to study the mechanism for the coordinated expression of ribosome biogenesis genes MPP10 and YJR003C in yeast
Sat Jan 01 00:00:00 UTC 2011
Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation.
BMC genomics
Grober OM,Mutarelli M,Giurato G,Ravo M,Cicatiello L,De Filippo MR,Ferraro L,Nassa G,Papa MF,Paris O,Tarallo R,Luo S,Schroth GP,Benes V,Weisz A
CAB1001 was used in western blot to investigate and compare the genomic targets of estrogen receptor beta and alpha
Fri Jan 14 00:00:00 UTC 2011
Coevolution within a transcriptional network by compensatory trans and cis mutations.
Genome research
Kuo D,Licon K,Bandyopadhyay S,Chuang R,Luo C,Catalana J,Ravasi T,Tan K,Ideker T
CAB1001 was used in ChIP assay to study the coevolution of the AP-1 transcriptional network in budding yeast
Wed Dec 01 00:00:00 UTC 2010
Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.
Journal of cell science
Frederiks F,van Welsem T,Oudgenoeg G,Heck AJ,Janzen CJ,van Leeuwen F
CAB1001 was used in western blot to investigate distinct enzymatic activities and substrate specificities of two DOT1 histone methyltransferases of Trypanosoma brucei
Wed Dec 01 00:00:00 UTC 2010
Stb3 plays a role in the glucose-induced transition from quiescence to growth in Saccharomyces cerevisiae.
Genetics
Liko D,Conway MK,Grunwald DS,Heideman W
CAB1001 was used in western blot to investigate the role of Stb3 in the growth transition in Saccharomyces cerevisiae
Thu Jul 01 00:00:00 UTC 2010
Identification of a hormone-regulated dynamic nuclear actin network associated with estrogen receptor alpha in human breast cancer cell nuclei.
Molecular & cellular proteomics : MCP
Ambrosino C,Tarallo R,Bamundo A,Cuomo D,Franci G,Nassa G,Paris O,Ravo M,Giovane A,Zambrano N,Lepikhova T,Jänne OA,Baumann M,Nyman TA,Cicatiello L,Weisz A
CAB1001 was used in western blot to study the association of estrogen receptor alpha with a nuclear actin network in human breast cancer cell nuclei
Tue Jun 01 00:00:00 UTC 2010
The eukaryotic translation elongation Factor 1Bgamma has a non-guanine nucleotide exchange factor role in protein metabolism.
The Journal of biological chemistry
Esposito AM,Kinzy TG
CAB1001 was used in western blot to investigate the role of the eukaryotic translation elongation factor 1B gamma in protein metabolism
Fri Dec 03 00:00:00 UTC 2010
An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Molecular cell
Li H,Motamedi MR,Yip CK,Wang Z,Walz T,Patel DJ,Moazed D
CAB1001 was used in western blot to investigate the function of an alpha motif at Tas3 C terminus in RITS cis spreading and heterochromatic gene silencing
Fri Apr 24 00:00:00 UTC 2009
Cryo-EM reveals promoter DNA binding and conformational flexibility of the general transcription factor TFIID.
Structure (London, England : 1993)
Elmlund H,Baraznenok V,Linder T,Szilagyi Z,Rofougaran R,Hofer A,Hebert H,Lindahl M,Gustafsson CM
CAB1001 was used in immunohistochemistry to perform structural and functional analysis of transcription factor IID
Wed Nov 11 00:00:00 UTC 2009
Identification of novel spartin-interactors shows spartin is a multifunctional protein.
Journal of neurochemistry
Milewska M,McRedmond J,Byrne PC
CAB1001 was used in western blot to identify novel spartin-interactors and their complexing with spartin
Sun Nov 01 00:00:00 UTC 2009
Different requirements of the SWI/SNF complex for robust nucleosome displacement at promoters of heat shock factor and Msn2- and Msn4-regulated heat shock genes.
Molecular and cellular biology
Erkina TY,Tschetter PA,Erkine AM
CAB1001 was used in ChIP assay to investigate the importance of the SWI/SNF complex in chromatin remodeling at promoters of heat shock factor and Msn2/4-regulated heat shock genes
Fri Feb 01 00:00:00 UTC 2008
A genome-wide role for CHD remodelling factors and Nap1 in nucleosome disassembly.
The EMBO journal
Walfridsson J,Khorosjutina O,Matikainen P,Gustafsson CM,Ekwall K
CAB1001 was used in Western blot to investigate the effect of CHD remodellers and Nap1 on nucleosome disassembly at promoters and coding regions
Wed Jun 20 00:00:00 UTC 2007
Hst3 is regulated by Mec1-dependent proteolysis and controls the S phase checkpoint and sister chromatid cohesion by deacetylating histone H3 at lysine 56.
The Journal of biological chemistry
Thaminy S,Newcomb B,Kim J,Gatbonton T,Foss E,Simon J,Bedalov A
CAB1001 was used in western blot to study the role of Hst3 in the S phase checkpoint
Fri Dec 28 00:00:00 UTC 2007
