Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TAS2R4.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bitter taste receptor T2R16; MGC163311; T2R16; T2R20; T2R4; tas2r4 {ECO:0000250|UniProtKB:Q9JKT3}; Taste receptor type 2 member 108; Taste receptor type 2 member 20; Taste receptor type 2 member 4
Gene Aliases: T2R16; T2r20; Tas2r108; Tas2r4
UniProt ID: (Rat) Q67ET0
Entrez Gene ID: (Rat) 554302
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