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Invitrogen
TAS2R41 Polyclonal Antibody
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Product Details
PA5-104309
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TAS2R41(Accession P59536), corresponding to amino acid residues L184-K234.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853619
Product Specific Information
Antibody detects endogenous levels of total TAS2R41.
Target Information
TAS2R41 is a receptor that may play a role in the perception of bitterness and belongs to the G-protein receptor superfamily. TAS2R41 is expressed mainly in taste receptor cells of the tongue and the palate eptithelia. Structurally, the TAS2R41 gene encodes a seven trans-membrane receptor protein and is clustered together with eight other taste receptor genes on chromosome 7. The compound chloramphenicol is an agonist for the TAS2R41 protein. Further, TAS2R41 may play a role in sensing the chemical composition of the gastrointestinal content. The activity of TAS2R41 may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. TAS2R41 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC119928; MGC119929; T2R12; T2R26; T2R41; T2R59; taste receptor rT2R12; Taste receptor type 2 member 126; Taste receptor type 2 member 41; Taste receptor type 2 member 59; taste receptor, type 2, member 41
Gene Aliases: mGR26; mt2r35; T2R12; T2R26; T2R41; T2R59; Tas2r12; Tas2r126; Tas2r26; TAS2R41
UniProt ID: (Human) P59536, (Rat) Q9JKE7, (Mouse) P59532
Entrez Gene ID: (Human) 259287, (Rat) 246219, (Mouse) 387353
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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