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Invitrogen
TAZ Polyclonal Antibody
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TAZ Antibody (PA5-85222) in IHC (P)
TAZ antibody [C2C3], C-term detects TAZ protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. TAZ antibody [C2C3], C-term (Product # PA5-85222) dilution: 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-85222
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Tafazzin/TAZ. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792365
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Chimpanzee (100%).
Positive Control: Synthetic peptide: 1:8,000.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy, hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction. Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ27390; HGNC:11577; OTTHUMP00000061673; Protein G4.5; Tafazzin; Taz; XAP-2; XX-FW83563B9.3
Gene Aliases: BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; TAFAZZIN; TAZ; Taz1
UniProt ID: (Human) Q16635
Entrez Gene ID: (Human) 6901
muscle contraction
heart development
skeletal muscle tissue development
hemopoiesis
cardiolipin biosynthetic process
mitochondrial respiratory chain complex I assembly
cardiolipin acyl-chain remodeling
cristae formation
mitochondrial ATP synthesis coupled electron transport
cardiac muscle tissue development
cardiac muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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