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Invitrogen
TAZ Polyclonal Antibody
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TAZ Antibody (PA5-95136) in WB
Western blot analysis of TAZ in Lane 1: rat skeletal muscle tissue lysate, Lane 2: rat heart tissue lysate, Lane 3: rat liver tissue lysate, Lane 4: HeLa cell lysate, Lane 5: SMMC cell lysate, Lane 6: SCG cell lysate. Samples were incubated with TAZ polyclonal antibody (Product # PA5-95136).
Product Details
PA5-95136
Product Specifications
Species Reactivity
Rat,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Tafazzin (162-178aa MDFILEKLNHGDWVHIF).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806941
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Skeletal Muscle Tissue, Rat Heart Tissue, Rat Liver Tissue, HELA Cell, SMMC Cell, SCG Cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy, hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction. Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Barth syndrome); cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; FLJ27390; HGNC:11577; OTTHUMP00000061673; Protein G4.5; Tafazzin; tafazzin (cardiomyopathy, dilated 3A (X-linked); tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome); Taz; XAP-2; XX-FW83563B9.3
Gene Aliases: 5031411C02Rik; 9130012G04Rik; AW107266; AW552613; BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; TAFAZZIN; TAZ; Taz1
UniProt ID: (Human) Q16635, (Mouse) Q810E8
Entrez Gene ID: (Human) 6901, (Rat) 363521, (Mouse) 66826
muscle contraction
inner mitochondrial membrane organization
heart development
skeletal muscle tissue development
biological_process
hemopoiesis
cardiolipin biosynthetic process
mitochondrial respiratory chain complex I assembly
cardiolipin acyl-chain remodeling
cristae formation
mitochondrial ATP synthesis coupled electron transport
cardiac muscle tissue development
cardiac muscle contraction
phosphatidylglycerol metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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