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Invitrogen
TBC1D17 Polyclonal Antibody
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Product Details
PA5-64361
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TBC1D17. Recombinant protein control fragment (Product #RP-103720).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2648255
Product Specific Information
Immunogen sequence: GVYLHTSAKK YQDRDSLIAG VIRVVEKDND VLLHWAPVEE AGDSTQILFS KKDSSGGDSC ASEEEPTFDP GYEPDWAVIS TVRPQLCHSE PTRGAEPSC
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 82%.
Target Information
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TBC1 domain family member 17; TBC1 domain family, member 17
Gene Aliases: TBC1D17
UniProt ID: (Human) Q9HA65
Entrez Gene ID: (Human) 79735
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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