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Invitrogen
TBCA Polyclonal Antibody
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TBCA Antibody (PA5-88944) in IHC (P)
Immunohistochemistry analysis of TBCA in paraffin-embedded mouse spinal cord. Samples were incubated with TBCA Polyclonal antibody (Product # PA5-88944) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-88944
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human TBCA (NP_0045981)
Conjugate
Form
Liquid
Concentration
1.21 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805241
Product Specific Information
Immunogen sequence: MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA; Positive Samples: OVCAR3, HeLa, 293T, U-87MG, Mouse testis; Cellular Location: Cytoplasm, cytoskeleton
Target Information
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CFA; chaperonin cofactor A; co-chaperonin associated with a- & b-tubulin; cofactor A; TCP1-chaperonin cofactor A; tubulin cofactor a; Tubulin-folding cofactor A; Tubulin-specific chaperone A
Gene Aliases: TBCA; Tbca13
UniProt ID: (Human) O75347, (Mouse) P48428, (Rat) Q6PEC1
Entrez Gene ID: (Human) 6902, (Mouse) 21371, (Rat) 366995
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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