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Product Details
MA5-37916
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1U1K5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TBR1 (Q16650)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897836
Product Specific Information
Positive Samples: Mouse brain, Rat brain
Immunogen sequence: MQLEHCLSPS IMLSKKFLNV SSSYPHSGGS ELVLHDHPII STTDNLERSS PLKKITRGMT NQSDTDNFPD SKDSPGDVQR SKLSPVLDGV SELRHSFDGS
Target Information
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: T-box brain gene 1; T-box brain protein 1; T-box, brain, 1-like; T-brain-1; TBR-1; TES-56
Gene Aliases: Tbr1
UniProt ID: (Mouse) Q64336
Entrez Gene ID: (Mouse) 21375, (Rat) 680427
conditioned taste aversion
transcription, DNA-templated
regulation of transcription, DNA-templated
specification of organ identity
regulation of gene expression
regulation of neuron projection development
amygdala development
commitment of neuronal cell to specific neuron type in forebrain
neuron differentiation
hindbrain development
positive regulation of transcription from RNA polymerase II promoter
regulation of axon guidance
axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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