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OriGene
TBX19 (Tpit) Monoclonal Antibody (OTI1C9), TrueMAB™
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FIGURE: 1 / 1
TBX19 (Tpit) Antibody (TA800675) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TBX19 (RC210787, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-TBX19. Positive lysates LY417491 (100 µg) and LC417491 (20 µg) can be purchased separately from OriGene.
Product Details
TA800675
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1C9
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-238 of human TBX19 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: T-box factor, pituitary; T-box protein 19; T-box transcription factor TBX19; TBS 19
Gene Aliases: dJ747L4.1; TBS19; TBX19; TPIT
UniProt ID: (Human) O60806
Entrez Gene ID: (Human) 9095
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
anatomical structure morphogenesis
pituitary gland development
regulation of cell proliferation
cell fate commitment
regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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