OriGene

TBX20 Monoclonal Antibody (OTI3D12), TrueMAB™

View all (14) TBX20 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

CF809355

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI3D12

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-340 of human TBX20 produced in E.coli.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

TBX20 is a member of the T-box transcription factor family expressed in the developing heart, eye, ventral neural tube, and limbs, indicating a possible role in regulating development of these tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: T-box protein 20; T-box transcription factor TBX20

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Gene Aliases: 9430010M06Rik; AL022859; ASD4; Tbx12; TBX20

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UniProt ID: (Human) Q9UMR3, (Mouse) Q9ES03

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Entrez Gene ID: (Human) 57057, (Mouse) 57246

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Function(s)
RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding RNA polymerase II transcription coactivator activity DNA binding transcription factor activity, sequence-specific DNA binding protein binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter patterning of blood vessels neuron migration heart looping embryonic heart tube morphogenesis outflow tract septum morphogenesis outflow tract morphogenesis tricuspid valve development aortic valve development aortic valve morphogenesis pulmonary valve formation endocardial cushion morphogenesis cardiac chamber formation cardiac right ventricle morphogenesis endocardial cushion formation cardiac septum development pericardium morphogenesis transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter muscle contraction multicellular organism development blood circulation cell proliferation dorsal/ventral pattern formation regulation of epithelial to mesenchymal transition negative regulation of SMAD protein complex assembly visceral motor neuron differentiation embryonic heart tube development foramen ovale closure embryonic heart tube elongation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cardiac muscle tissue morphogenesis positive regulation of cardiac muscle cell proliferation atrial septum morphogenesis pulmonary vein morphogenesis endoderm formation lateral mesoderm formation
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