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Proteintech
TBX6 Polyclonal Antibody
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Product Details
12447-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TBX6 Fusion Protein Ag3050 (87-436 aa encoded by BC026031)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SLPGVSLSL ENRELWKEFS SVGTEMIITK AGRRMFPACR VSVTGLDPEA RYLFLLDVIP VDGARYRWQG RRWEPSGKAE PRLPDRVYIH PDSPATGAHW MRQPVSFHRV KLTNSTLDPH GHLILHSMHK YQPRIHLVRA AQLCSQHWGG MASFRFPETT FISVTAYQNP QITQLKIAAN PFAKGFRENG RNCKRERDAR VKRKLRGPEP AATEAYGSGD TPGGPCDSTL GGDIRESDPE QAPAPGEATA APAPLCGGPS AEAYLLHPAA FHGAPSHLPT RSPSFPEAPD SGRSAPYSAA FLELPHGSGG SGYPAAPPAV PFAPHFLQGG PFPLPYTAPG GYLDVGSKPM Y (87-436 aa encoded by BC026031)
Target Information
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: rib-vertebrae; T-box protein 6; T-box transcription factor TBX6
Gene Aliases: rv; SCDO5; TBX6
UniProt ID: (Human) O95947, (Mouse) P70327, (Rat) D3ZJK7
Entrez Gene ID: (Human) 6911, (Mouse) 21389, (Rat) 365371
negative regulation of transcription from RNA polymerase II promoter
mesoderm formation
cell fate specification
transcription, DNA-templated
mesoderm development
anatomical structure morphogenesis
negative regulation of neuron projection development
negative regulation of neuron maturation
signal transduction involved in regulation of gene expression
somite rostral/caudal axis specification
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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