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Invitrogen
TBX6 Polyclonal Antibody
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FIGURE: 1 / 1
TBX6 Antibody (PA5-95860) in WB
Western blot analysis of TBX6 in various lysates. Samples were incubated with TBX6 Polyclonal antibody (Product # PA5-95860) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-95860
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TBX6 (NP_0045992)
Conjugate
Form
Liquid
Concentration
0.97 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807662
Product Specific Information
Immunogen sequence: MYHPRELYPS LGAGYRLGPA QPGADSSFPP ALAEGYRYPE LDTPKLDCFL SGMEAAPRTL AAHPPLPLLP PAMGTEPAPS APEALHSLPG VSLSLENREL WKEFSSVGTE MIITKAGRRM FPACRVSVTG LDPEARYLFL LDVIPVDGAR YRWQGRRWEP SGKAEPRLPD RVYIHPDSPA TGAHWMRQPV SFHRVKLTNS TLDPHGHLIL HSMHKYQPRI HLVRAAQLCS QHWGGMASFR FPETTFISVT AYQNPQITQL KIAANPFAKG FRENGRNCKR
Target Information
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: rib-vertebrae; T-box protein 6; T-box transcription factor TBX6
Gene Aliases: rv; SCDO5; TBX6
UniProt ID: (Human) O95947, (Mouse) P70327, (Rat) D3ZJK7
Entrez Gene ID: (Human) 6911, (Mouse) 21389, (Rat) 365371
negative regulation of transcription from RNA polymerase II promoter
mesoderm formation
cell fate specification
transcription, DNA-templated
mesoderm development
anatomical structure morphogenesis
negative regulation of neuron projection development
negative regulation of neuron maturation
signal transduction involved in regulation of gene expression
somite rostral/caudal axis specification
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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