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Invitrogen
TBXA2R beta Polyclonal Antibody
Product Details
PA5-143070
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-PFEPPTGKALSRKD.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2933709
Product Specific Information
Additional Information: This antibody is expected to recognize the reported isoform beta (NP_963998.2) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. This target is specific to isoform beta, endothelial receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Prostanoid TP receptor; Thromboxane A2 receptor; TXA2-R
Gene Aliases: BDPLT13; TBXA2R; TXA2-R
UniProt ID: (Human) P21731
Entrez Gene ID: (Human) 6915
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
response to nutrient
second-messenger-mediated signaling
response to lipopolysaccharide
thromboxane A2 signaling pathway
response to drug
positive regulation of GTPase activity
positive regulation of angiogenesis
positive regulation of blood pressure
positive regulation of vasoconstriction
positive regulation of smooth muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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