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Invitrogen
TC10 Polyclonal Antibody
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Product Details
PA5-30573
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human TC10. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548047
Product Specific Information
Recommended positive controls: HepG2.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (94%), Xenopus Tropicalis (94%), Chicken (96%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 42; ras homolog gene family, member Q; Ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; Rho-related GTP-binding protein RhoQ
Gene Aliases: ARHQ; HEL-S-42; RASL7A; RHOQ; TC10; TC10A
UniProt ID: (Human) P17081
Entrez Gene ID: (Human) 23433
small GTPase mediated signal transduction
insulin receptor signaling pathway
regulation of cell shape
cortical actin cytoskeleton organization
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
GTP metabolic process
positive regulation of glucose import
regulation of small GTPase mediated signal transduction
positive regulation of filopodium assembly
negative regulation of establishment of protein localization to plasma membrane
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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