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Proteintech
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Immunogen sequence: MEDEVVRFA KKMDKMVQKK NAAGALDLLK ELKNIPMTLE LLQSTRIGMS VNAIRKQSTD EEVTSLAKSL IKSWKKLLDG PSTEKDLDEK KKEPAITSQN SPEAREESTS SGNVSNRKDE TNARDTYVSS FPRAPSTSDS VRLKCREMLA AALRTGDDYI AIGADEEELG SQIEEAIYQE IRNTDMKYKN RVRSRISNLK DAKNPNLRKN VLCGNIPPDL FARMTAEEMA SDELKEMRKN LTKEAIREHQ MAKTGGTQTD LFTCGKCKKK NCTYTQVQTR SADEPMTTFV VCNECGNRWK FC (1-301 aa encoded by BC072460)
TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: transcription elongation factor A (SII), 1; Transcription elongation factor A protein 1; Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.o; transcription factor IIS
Gene Aliases: GTF2S; S-II; SII; TCEA; TCEA1; Tceat; TF2S; TFIIS
UniProt ID: (Human) P23193, (Mouse) P10711, (Rat) Q4KLL0
Entrez Gene ID: (Human) 6917, (Mouse) 21399, (Rat) 362479
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