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TCEA1 Antibody (MA5-53266) in ICC/IF
Immunocytochemistry analysis of TCEA1 in HepG2 cells. Nuclei were stained blue with DAPI; TCEA1 recombinant monoclonal antibody (Product # MA5-53266) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar: 20 μm.
Product Details
MA5-53266
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB2335
Immunogen
A synthesized peptide derived from human TCEA1 (210-245AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3247739
Target Information
TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: transcription elongation factor A (SII), 1; Transcription elongation factor A protein 1; Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.o; transcription factor IIS
Gene Aliases: GTF2S; S-II; SII; TCEA; TCEA1; Tceat; TF2S; TFIIS
UniProt ID: (Human) P23193, (Mouse) P10711, (Rat) Q4KLL0
Entrez Gene ID: (Human) 6917, (Mouse) 21399, (Rat) 362479
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
erythrocyte differentiation
regulation of DNA-templated transcription, elongation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
positive regulation of exoribonuclease activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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