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Immunogen sequence: MMGKEEEIAR IARRLDKMVT KKSAEGAMDL LRELKAMPIT LHLLQSTRVG
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
The protein encoded by TCEA2 is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Testis-specific S-II; transcription elongation factor A (SII), 2; Transcription elongation factor A protein 2; Transcription elongation factor S-II protein 2; transcription elongation factor TFIIS.1; Transcription elongation factor TFIIS.l
Gene Aliases: TCEA2; TFIIS
UniProt ID: (Human) Q15560
Entrez Gene ID: (Human) 6919
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