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Invitrogen
TCN2 Polyclonal Antibody
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TCN2 Antibody (PA5-120946) in WB
Western blot analysis of TCN2 in extracts of various cell lines. Samples were incubated with TCN2 Polyclonal antibody (Product # PA5-120946) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-120946
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-250 of human TCN2 (NP_001171655.1).
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914518
Product Specific Information
Positive test controls include: SW480, MCF7, A-549, U-251MG, Mouse kidney, Mouse lung. The target is usually found in the following locations: Secreted.
Immunogen sequence: EMCEIPEMDS HLVEKLGQHL LPWMDRLSLE HLNPSIYVGL RLSSLQAGTK EDLYLHSLKL GYQQCLLGSA FSEDDGDCQG KPSMGQLALY LLALRANWHD HKGHPHTSYY QYGLGILALC LHQKRVHDSV VDKLLYAVEP FHQGHHSVDT AAMAGLAFTC LKRSNFNPGR RQRITMAIRT VREEILKAQT PEGHFGNVYS TPLALQFLMT SPMRGAELGT ACLKARVALL AS
Target Information
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: macrocytic anemia; TC II; TC TC D22S676; TC-2; TCII; Transcobalamin II; transcobalamin II; macrocytic anemia; Transcobalamin-2; vitamin B12-binding protein 2
Gene Aliases: AW208754; D22S676; D22S750; II; TC; TC II; TC-2; TC2; TCII; Tcn-2; TCN2
UniProt ID: (Human) P20062, (Mouse) O88968
Entrez Gene ID: (Human) 6948, (Mouse) 21452
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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