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Invitrogen
TCP1 epsilon Polyclonal Antibody
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FIGURE: 1 / 9
TCP1 epsilon Antibody (PA5-78955) in ICC/IF
Immunocytochemistry analysis of CCT5 using anti-CCT5 antibody (Product # PA5-78955) . CCT5 was detected in a section of U2OS cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 2μg/mL rabbit anti-CCT5 antibody (Product # PA5-78955) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbit IgG... View More
Product Details
PA5-78955
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human CCT5 recombinant protein (Position: L443-K535).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.01mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746071
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human MCF-7 whole cell, human SiHa whole cell, human A549 whole cell, human 293T whole cell, human CACO-2 whole cell, human PC-3 whole cell, human U20S whole cell, rat testis tissue, mouse testis tissue, mouse liver tissue. IHC: mouse ovary tissue, rat ovary tissue, human intestinal cancer tissue. ICC/IF: U20S cell, LOVO Cell. Flow: A431 cell.
Target Information
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCT-epsilon; Chaperonin containing T-complex polypeptide 1 subunit 5; chaperonin containing TCP1, subunit 5 (epsilon); chaperonin subunit 5 (epsilon); epididymis secretory protein Li 69; T-complex protein 1 subunit epsilon; TCP-1-epsilon
Gene Aliases: CCT-epsilon; CCT5; CCTE; HEL-S-69; KIAA0098; mKIAA0098; PNAS-102; TCP-1-epsilon; TCPE
UniProt ID: (Human) P48643, (Mouse) P80316, (Rat) Q68FQ0
Entrez Gene ID: (Human) 22948, (Mouse) 12465, (Rat) 294864
protein folding
binding of sperm to zona pellucida
response to virus
positive regulation of telomere maintenance via telomerase
protein stabilization
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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