Invitrogen

TCR DO11.10 Monoclonal Antibody (KJ1-26), APC

Product Details

MA5-17660

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

0.5 µg/1x10^6 cells

View 10 publications 10 publications

Miscellaneous PubMed (MISC)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

KJ1-26

Immunogen

T cell hybridoma, D011.10

Conjugate

APC APC APC

Excitation/Emission Max

651/660 nm View spectra

Form

Liquid

Concentration

0.1 mg/mL

Purification

Protein G

Storage buffer

PBS with 4-5mg/mL BSA

Contains

0.02% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2539050

Product Specific Information

MA5-17660 targets D011.10 TCR in FACS applications and shows reactivity with Mouse samples.

The MA5-17660 immunogen is t cell hybridoma, D011.10.

Target Information

TCR DO11 (DO11.10) is a receptor found on lymphocytes of DO11.10 transgenic mice and T-cell receptors of BALB/c-derived DO11.10 and DO11.10.24 T cell hybridomas. The DO11.10 TCR recognizes a C-terminal ovalbumin peptide (OVA 323-339) in the context of I-Ad major histocompatibility molecules. The use of antibodies against DO11.10 have proven to be instrumental in describing many of the intricate details of T cell immunity, including T cell activation, development, and function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

Accumulation of effector CD4 T cells during type 2 immune responses is negatively regulated by Stat6.

Journal of immunology (Baltimore, Md. : 1950)

King SB,Knorn AM,Ohnmacht C,Voehringer D

MA5-17660 was used in flow cytometry to investigate the effect of Stat6 in T cell expansion, survival, and recruitment to the lung

Tue Jan 15 00:00:00 UTC 2008

Influenza A virus elevates active cathepsin B in primary murine DC.

International immunology

Burster T,Giffon T,Dahl ME,Björck P,Bogyo M,Weber E,Mahmood K,Lewis DB,Mellins ED

MA5-17660 was used in flow cytometry to suggest that the influenza A virus affects the MHC class II antigen-processing pathway

Tue May 01 00:00:00 UTC 2007

Structure and duration of contact between dendritic cells and T cells are controlled by T cell activation state.

European journal of immunology

Rothoeft T,Balkow S,Krummen M,Beissert S,Varga G,Loser K,Oberbanscheidt P,van den Boom F,Grabbe S

MA5-17660 was used in flow cytometry to characterize T cells interactions with dendritic cells

Fri Dec 01 00:00:00 UTC 2006

CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia.

Journal of immunology (Baltimore, Md. : 1950)

Vanasek TL,Nandiwada SL,Jenkins MK,Mueller DL

MA5-17660 was used in flow cytometry to study ineffective T cell clonal anergy induction in nu/nu mice

Mon May 15 00:00:00 UTC 2006

Divergent generation of heterogeneous memory CD4 T cells.

Journal of immunology (Baltimore, Md. : 1950)

Moulton VR,Bushar ND,Leeser DB,Patke DS,Farber DL

MA5-17660 was used in flow cytometry to elucidate the generation of memory CD4 T cells

Sat Jul 15 00:00:00 UTC 2006

Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help.

Blood

Hardtke S,Ohl L,Förster R

MA5-17660 was used in flow cytometry to report that CCR7 and CXCR5 determine the positioning and proper function of follicular T helper cells

Thu Sep 15 00:00:00 UTC 2005

Increased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation.

Journal of leukocyte biology

Cruise MW,Melief HM,Lukens J,Soguero C,Hahn YS

MA5-17660 was used in flow cytometry to elucidate the role of hepatitis C virus core-expressing T cells in liver inflammation

Mon Aug 01 00:00:00 UTC 2005

A role for CD28 in lymphopenia-induced proliferation of CD4 T cells.

Journal of immunology (Baltimore, Md. : 1950)

Hagen KA,Moses CT,Drasler EF,Podetz-Pedersen KM,Jameson SC,Khoruts A

MA5-17660 was used in flow cytometry to characterize T cells during lymphopenia-induced proliferation

Wed Sep 15 00:00:00 UTC 2004

Indirect minor histocompatibility antigen presentation by allograft recipient cells in the draining lymph node leads to the activation and clonal expansion of CD4+ T cells that cause obliterative airways disease.

Journal of immunology (Baltimore, Md. : 1950)

Richards DM,Dalheimer SL,Ehst BD,Vanasek TL,Jenkins MK,Hertz MI,Mueller DL

MA5-17660 was used in flow cytometry to investigate minor histocompatibility antigen-induced chronic allograft rejection.

Mon Mar 15 00:00:00 UTC 2004

Vitamin A deficiency increases the in vivo development of IL-10-positive Th2 cells and decreases development of Th1 cells in mice.

The Journal of nutrition

Stephensen CB,Jiang X,Freytag T

MA5-17660 was used in flow cytometry to test if vitamin A deficiency affects development of Th1/Th2 memory cell phenotype in vivo

Fri Oct 01 00:00:00 UTC 2004

A limited antigen-specific cellular response is sufficient for the early control of Mycobacterium tuberculosis in the lung but is insufficient for long-term survival.

Infection and immunity

Turner J,Dobos KM,Keen MA,Frank AA,Ehlers S,Orme IM,Belisle JT,Cooper AM

MA5-17660 was used in flow cytometry to identify Rv1411c as an important and potent inducer of protective T cells within the lungs of mice infected with Mycobacterium tuberculosis

Thu Jul 01 00:00:00 UTC 2004

Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation.

The Journal of experimental medicine

Reinhardt RL,Bullard DC,Weaver CT,Jenkins MK

MA5-17660 was used in flow cytometry to study the migration of antigen-specific T cells to nonlymphoid tissues.

Mon Mar 17 00:00:00 UTC 2003

Bioinformatics

Protein Aliases: D011.10

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Gene Aliases: Tcralpha

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Entrez Gene ID: (Mouse) 21473

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TCR DO11.10 Monoclonal Antibody (KJ1-26), APC

Product Details

MA5-17660

Flow Cytometry (Flow)

Miscellaneous PubMed (MISC)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

How to use the Panel Builder

Bioinformatics

Performance Guarantee

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