Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 3
Positive Samples: HeLa, 22Rv1, Rat ovary
Immunogen sequence: MDLENKVKKM GLGHEQGFGA PCLKCKEKCE GFELHFWRKI CRNCKCGQEE HDVLLSNEED RKVGKLFEDT KYTTLIAKLK SDGIPMYKRN VMILTNPVAA KKNVSINTVT YEWAPPVQNQ ALARQYMQML PKEKQPVAGS EGAQYRKKQL AKQLPAHDQD PSKCHELSPR EVKEMEQFVK KYKSEALGVG DVKLPCEMDA QGPKQMNIPG GDRSTPAAVG AMEDKSAEHK RTQYSCYCCK LSMKEGDPAI YAERAGYDKL
TES maps to a common fragile site on chromosome 7q31.2 designated FRA7G and this gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of the TES gene and Cancer-associated chromosomal changes often involve regions containing fragile sites involving the TES gene.
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Protein Aliases: TESS; Testin; testis derived transcript (3 LIM domains)
Gene Aliases: TES; TESS; TESS-2
UniProt ID: (Human) Q9UGI8, (Rat) Q2LAP6
Entrez Gene ID: (Human) 26136, (Rat) 500040
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