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TESC Polyclonal Antibody

TESC Antibody in Immunocytochemistry (ICC/IF)

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TESC Antibody (11125-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed A549 cells using (Product # 11125-1-AP) (TESC antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

TESC Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

11125-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TESC Fusion Protein Ag1596 (1-214 aa encoded by BC015221)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGAAHSASE EVRELEGKTG FSSDQIEQLH RRFKQLSGDQ PTIRKENFNN VPDLELNPIR SKIVRAFFDN RNLRKGPSGL ADEINFEDFL TIMSYFRPID TTMDEEQVEL SRKEKLRFLF HMYDSDSDGR ITLEEYRNVV EELLSGNPHI EKESARSIAD GAMMEAASVC MGQMEPDQVY EGITFEDFLK IWQGIDIETK MHVRFLNMET MALCH (1-214 aa encoded by BC015221)

Target Information

Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TESC promotes differentiated thyroid cancer development by activating ERK and weakening NIS and radioiodine uptake.

Endocrine

Guo Y,Cai Y,Song F,Zhu L,Hu Y,Liu Y,Ma W,Ge J,Zeng Q,Ding L,Li L,Zheng G,Ge M

Fri Sep 01 00:00:00 UTC 2023

Tescalcin promotes highly invasive papillary thyroid microcarcinoma by regulating FOS/ERK signaling pathway.

BMC cancer

Zou X,Zhou Q,Nie Y,Gou J,Yang J,Zhu J,Li Z,Gong Y

Tue May 31 00:00:00 UTC 2022

The Expression Profile, Clinical Application and Potential Tumor Suppressing Mechanism of hsa_circ_0001675 in Head and Neck Carcinoma.

Frontiers in oncology

Cao Y,Ye D,Shen Z,Li Z,Li Q,Rong H

Sat Jul 16 00:00:00 UTC 2022

TESC Promotes TGF-α/EGFR-FOXM1-Mediated Tumor Progression in Cholangiocarcinoma.

Cancers

Hsieh CH,Chu CY,Lin SE,Yang YSH,Chang HS,Yen Y

Wed Apr 29 00:00:00 UTC 2020

Tescalcin is an unfavorable prognosis factor that regulats cell proliferation and survival in hepatocellular carcinoma patients.

Cancer communications (London, England)

Zhou ZG,Chen JB,Zhang RX,Ye L,Wang JC,Pan YX,Wang XH,Li WX,Zhang YJ,Xu L,Chen MS

Sat Aug 01 00:00:00 UTC 2020

Tescalcin is an unfavorable prognosis factor that regulats cell proliferation and survival in hepatocellular carcinoma patients.

Cancer communications (London, England)

Zhou ZG,Chen JB,Zhang RX,Ye L,Wang JC,Pan YX,Wang XH,Li WX,Zhang YJ,Xu L,Chen MS

Sat Aug 01 00:00:00 UTC 2020

Differential expression of tescalcin by modification of promoter methylation controls cell survival in gastric cancer cells.

Oncology reports

Kim TW,Han SR,Kim JT,Yoo SM,Lee MS,Lee SH,Kang YH,Lee HG

Sat Jun 01 00:00:00 UTC 2019

Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis.

Genome biology

Fan J,Xing Y,Wen X,Jia R,Ni H,He J,Ding X,Pan H,Qian G,Ge S,Hoffman AR,Zhang H,Fan X

Tue Jul 14 00:00:00 UTC 2015

Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis.

Genome biology

Fan J,Xing Y,Wen X,Jia R,Ni H,He J,Ding X,Pan H,Qian G,Ge S,Hoffman AR,Zhang H,Fan X

Tue Jul 14 00:00:00 UTC 2015

The EF-hand calcium-binding protein tescalcin is a potential oncotarget in colorectal cancer.

Oncotarget

Kang YH,Han SR,Kim JT,Lee SJ,Yeom YI,Min JK,Lee CH,Kim JW,Yoon SR,Yoon DY,Hong KS,Hwang GS,Kim HC,Lee YH,Lee HG

Wed Apr 30 00:00:00 UTC 2014

CHP1-mediated NHE1 biosynthetic maturation is required for Purkinje cell axon homeostasis.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Liu Y,Zaun HC,Orlowski J,Ackerman SL

Wed Jul 31 00:00:00 UTC 2013

CHP1-mediated NHE1 biosynthetic maturation is required for Purkinje cell axon homeostasis.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Liu Y,Zaun HC,Orlowski J,Ackerman SL

Wed Jul 31 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: Calcineurin B homologous protein 3; calcineurin-like EF hand protein 3; CHP3; TE-1; Tescalcin; TSC

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Gene Aliases: 1010001A17Rik; 2410011K10Rik; CHP3; RGD1566317; TE-1; TESC; TSC

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UniProt ID: (Human) Q96BS2, (Mouse) Q9JKL5

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Entrez Gene ID: (Human) 54997, (Mouse) 57816, (Rat) 288689

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Function(s)

magnesium ion binding protein kinase inhibitor activity calcium ion binding protein binding phosphatase inhibitor activity protein homodimerization activity metal ion binding

Process(es)

transport cellular sodium ion homeostasis negative regulation of cell proliferation positive regulation of gene expression protein transport cell differentiation positive regulation of granulocyte differentiation positive regulation of sodium:proton antiporter activity regulation of cell adhesion mediated by integrin megakaryocyte development negative regulation of catalytic activity positive regulation of megakaryocyte differentiation positive regulation of transcription, DNA-templated protein stabilization protein maturation cellular response to retinoic acid protein targeting to plasma membrane male gonad development megakaryocyte differentiation negative regulation of protein kinase activity

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TESC Polyclonal Antibody

TESC Antibody (11125-1-AP) in ICC/IF

Product Details

11125-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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