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Invitrogen
TESC Polyclonal Antibody
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FIGURE: 1 / 1
TESC Antibody (PA5-97146) in WB
Western blot analysis of TESC in extracts of various cell lines. Samples were incubated with TESC Polyclonal antibody (Product # PA5-97146) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-97146
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 135-214 of human TESC (NP_0603693)
Conjugate
Form
Liquid
Concentration
1.65 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808948
Product Specific Information
Immunogen sequence: YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME PDQVYEGITF EDFLKIWQGI DIETKMHVRF LNMETMALCH; Positive Samples: HeLa, U87, 293T; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Lipid-anchor, Membrane, Nucleus, lamellipodium, ruffle membrane
Target Information
Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcineurin B homologous protein 3; calcineurin-like EF hand protein 3; Tescalcin; TSC
Gene Aliases: CHP3; TESC; TSC
UniProt ID: (Human) Q96BS2
Entrez Gene ID: (Human) 54997
negative regulation of protein kinase activity
negative regulation of cell proliferation
positive regulation of gene expression
cell differentiation
positive regulation of granulocyte differentiation
positive regulation of sodium:proton antiporter activity
regulation of cell adhesion mediated by integrin
positive regulation of megakaryocyte differentiation
positive regulation of transcription, DNA-templated
protein stabilization
protein maturation
cellular response to retinoic acid
protein targeting to plasma membrane
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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