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Proteintech
TESK2 Polyclonal Antibody
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Product Details
17414-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TESK2 Fusion Protein Ag10964 (190-542 aa encoded by BC033085)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GYSAVVADF GLAEKIPDVS MGSEKLAVVG SPFWMAPEVL RDEPYNEKAD VFSYGIILCE IIARIQADPD YLPRTEMDPK LRPSFVEIGK TLEEILSRLQ EEEQERDRKL QPTARGLLEK APGVKRLSSL DDKIPHKSPC PRRTIWLSRS QSDIFSRKPP RTVSVLDPYY RPRDGAARTP KVNPFSARQD LMGGKIKFFD LPSKSVISLV FDLDAPGPGT MPLADWQEPL APPIRRWCSL PGSPEFLHQE ACPFVGREES LSDGPPPRLS SLKYRVKEIP PFRASALPAA QAHEAMDCSI LQEENGFGSR PQGTSPCPAG ASEEMEVEER PAGSTPATFS TSGIGLQTQG KQDG (190-542 aa encoded by B C033085)
Target Information
TESK2 or testis-specific kinase 2 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. The kinase domain of TESK2 is structurally similar to the kinase domain of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). TESK2 is predominantly expressed in testis and prostate and plays an important role in spermatogenesis. TESK2 phosphorylates cofilin specifically at Ser-3 and induces formation of actin stress fibers and focal adhesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dual specificity testis-specific protein kinase 2; Testicular protein kinase 2
Gene Aliases: TESK2
UniProt ID: (Human) Q96S53, (Rat) Q924U5, (Mouse) Q8VCT9
Entrez Gene ID: (Human) 10420, (Rat) 170908, (Mouse) 230661
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
metal ion binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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