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Invitrogen
TESPA1 Polyclonal Antibody
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Product Details
PA5-46497
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human TESPA1 (aa 394-443).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610598
Product Specific Information
Peptide sequence: SLPIEDPQWS TDPAQIRREL CSLPATNTET HPAKDETFWK RKSRARKSLF
Sequence homology: Dog: 93%; Horse: 100%; Human: 100%; Pig: 100%; Rabbit: 86%
Target Information
TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein TESPA1; thymocyte expressed; Thymocyte-expressed positive selection-associated protein 1
Gene Aliases: HSPC257; KIAA0748; TESPA1
UniProt ID: (Human) A2RU30
Entrez Gene ID: (Human) 9840
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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