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FIGURE: 1 / 1
TET3 Antibody (MA5-51207) in WB
Western blot analysis of TET3 in extracts from Neuro-2a cells. Samples were incubated with TET3 Recombinant monoclonal antibody (Product # MA5-51207) using a dilution of 1:20,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
MA5-51207
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6I7Y2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of mouse TET3 (Q8BG87).
Conjugate
Form
Liquid
Concentration
1.69 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3093110
Product Specific Information
Immunogen sequence: MSQFQVPLAV QPDLSGLYDF PQGQVMVGGF QGPGLPMAGS ETQLRGGGDG RKKRKRCGTC DPCRRLENCG SCTSCTNRRT HQICKLRKCE VLKKKAGLLK EVEINAREGT GPWAQGATVK TGSELSPVDG PVPGQMDSGP VYHGDSRQLS TSGAPVNGAR EPAGPGLLGA AGPWRVDQKP DWEAASGPTH AARLEDAHDL VAFSAVAEAV SSYGALSTRL YETFNREMSR EAGSNGRGPR PESCSEGSED LDTLQTALAL ARHGMKPPNC TCDGPECPDF LEWLE
Target Information
TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; Tet methylcytosine deoxygenase 3 isoform; tet oncogene family member 3
Gene Aliases: B430006D22Rik; BC037432; D230004J03Rik; Tet3
UniProt ID: (Mouse) Q8BG87
Entrez Gene ID: (Mouse) 194388
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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