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Invitrogen
TFAP2D Polyclonal Antibody
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FIGURE: 1 / 3
TFAP2D Antibody (PA5-100768) in ICC/IF
Immunocytochemistry analysis of TFAP2D in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with TFAP2D polyclonal antibody (Product # PA5-100768) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100768
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TFAP2D(Accession Q7Z6R9), corresponding to amino acid residues D303-S353.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850271
Product Specific Information
Antibody detects endogenous levels of total TFAP2D.
Target Information
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activating enhancer binding protein 2 beta-like 1; activating enhancer-binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP-2 like; AP2-delta; TFAP2D; transcription factor AP-2 beta (activating enhancer binding protein 2 beta)-like 1; transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)-like 1; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta
Gene Aliases: Tcfap2d; TFAP2BL1; TFAP2D
UniProt ID: (Human) Q7Z6R9, (Mouse) Q91ZK0
Entrez Gene ID: (Human) 83741, (Rat) 301284, (Mouse) 226896
transcription, DNA-templated
regulation of cell proliferation
negative regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
anatomical structure development
inferior colliculus development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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