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TFAP2E Antibody (H00339488-B01P) in WB
Western Blot analysis of TFAP2E expression in transfected 293T cell line (H00339488-T01) by TFAP2E MaxPab polyclonal antibody.
Lane 1: TFAP2E transfected lysate(47.74 KDa).
Lane 2: Non-transfected lysate.
Lane 1: TFAP2E transfected lysate(47.74 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00339488-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TFAP2E (NP_848643.1, 1 a.a. approximately 434 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MERPDGLGAA AGGARLSSLP QAAYGPAPPL CHTPAATAAA EFQPPYFPPP YPQPPLPYGQ APDAAAAFPH LAGDPYGGLA PLAQPQPPQA AWAAPRAAAR AHEEPPGLLA PPARALGLDP RRDYATAVPR LLHGLADGAH GLADAPLGLP GLAAAPGLED LQAMDEPGMS LLDQSVIKKV PIPSKASSLS ALSLAKDSLV GGITNPGEVF CSVPGRLSLL SSTSKYKVTV GEVQRRLSPP ECLNASLLGG VLRRAKSKNG GRCLRERLEK IGLNLPAGRR KAANVTLLTS LVEGEAVHLA RDFGYVCETE FPAKAAAEYL CRQHADPGEL HSRKSMLLAA KQICKEFADL MAQDRSPLGN SRPALILEPG VQSCLTHFSL ITHGFGGPAI CAALTAFQNY LLESLKGLDK MFLSSVGSGH GETKASEKDA KHRK
Target Information
TFAP2E is the sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 epsilon may play a role in the development of the CNS and in cartilage differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating enhancer-binding protein 2-epsilon; adaptor-related protein complex 2, epsilon subunit; AP2-epsilon; MGC49007; TFAP2E; transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon); Transcription factor AP-2-epsilon
Gene Aliases: AP2E; TFAP2E
UniProt ID: (Human) Q6VUC0
Entrez Gene ID: (Human) 339488
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein homodimerization activity
protein heterodimerization activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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