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Invitrogen
TFB1M Polyclonal Antibody
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FIGURE: 1 / 4
TFB1M Antibody (PA5-98190) in ICC/IF
Immunofluorescent analysis of TFB1M in HepG2 cells using a TFB1M polyclonal antibody (Product # PA5-98190) at a dilution of 1:166. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L). Cells were counter-stained with DAPI.
Product Details
PA5-98190
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Dimethyladenosine transferase 1, mitochondrial protein (59-194AA)
Conjugate
Form
Liquid
Concentration
3.43 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2812804
Target Information
The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dimethyladenosine transferase 1, mitochondrial; h-mtTFB; h-mtTFB1; homolog of yeast mitochondrial transcription factor B; hTFB1M; Mitochondrial 12S rRNA dimethylase 1; mitochondrial dimethyladenosine transferase 1; Mitochondrial transcription factor B1; OTTHUMP00000017473; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1
Gene Aliases: CGI-75; CGI75; mtTFB; mtTFB1; TFB1M
UniProt ID: (Human) Q8WVM0
Entrez Gene ID: (Human) 51106
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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