Product References
Autophagy impairment is involved in midazolam-induced lipid droplet accumulation and consequent phagocytosis decrease in BV2 cells.
Biochemical and biophysical research communications
Zhu XL,Zhang HW,Peng WJ,Gao S,Yang ZL,Zhang JQ,Liu XS
Sun Feb 05 00:00:00 UTC 2023
Restoration of c-Src/Fyn Proteins Rescues Mitochondrial Dysfunction in Huntington's Disease.
Antioxidants & redox signaling
Fão L,Coelho P,Duarte L,Vilaça R,Hayden MR,Mota SI,Rego AC
Sun Jan 01 00:00:00 UTC 2023
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
Experimental cell research
He W,Tong G,Fan H,Zhen C,Zeng L,Xue L,Chen J,Sun Z,He P
Wed Feb 15 00:00:00 UTC 2023
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
Experimental cell research
He W,Tong G,Fan H,Zhen C,Zeng L,Xue L,Chen J,Sun Z,He P
Wed Feb 15 00:00:00 UTC 2023
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
Food & function
Meng Z,Lu J,Ge G,Wang G,Zhang R,Li Y,Guan S,Lu J
Tue Jan 03 00:00:00 UTC 2023
TFEB attenuates hyperglycemia-induced retinal capillary endothelial cells injury via autophagy regulation.
Cell biology international
Cheng Y,Fan H,Liu K,Liu J,Zou H,You Z
Thu Jun 01 00:00:00 UTC 2023
TFEB attenuates hyperglycemia-induced retinal capillary endothelial cells injury via autophagy regulation.
Cell biology international
Cheng Y,Fan H,Liu K,Liu J,Zou H,You Z
Thu Jun 01 00:00:00 UTC 2023
TFEB attenuates hyperglycemia-induced retinal capillary endothelial cells injury via autophagy regulation.
Cell biology international
Cheng Y,Fan H,Liu K,Liu J,Zou H,You Z
Thu Jun 01 00:00:00 UTC 2023
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.
Acta pharmacologica Sinica
Li ZB,Jiang L,Ni JD,Xu YH,Liu F,Liu WM,Wang SG,Liu ZQ,Wang CY
Thu Jun 01 00:00:00 UTC 2023
Acrylamide interferes with autophagy and induces apoptosis in Neuro-2a cells by interfering with TFEB-regulated lysosomal function.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Pang P,Zhang X,Yuan J,Yan H,Yan D
Sat Jul 01 00:00:00 UTC 2023
Acrylamide interferes with autophagy and induces apoptosis in Neuro-2a cells by interfering with TFEB-regulated lysosomal function.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Pang P,Zhang X,Yuan J,Yan H,Yan D
Sat Jul 01 00:00:00 UTC 2023
KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau through m6A-dependent regulation of STUB1.
Free radical biology & medicine
Tang Z,Cao J,Yao J,Fan X,Zhao J,Zhao M,Duan Q,Han B,Duan S
Wed Feb 01 00:00:00 UTC 2023
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Ecotoxicology and environmental safety
Zhang H,Xie Z,Peng Y,Xie A,Fu C,Zheng D,Cai Z,Zhong J,Ming Q,Li M,Lu R,Liu X,Chen J
Wed Mar 01 00:00:00 UTC 2023
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Ecotoxicology and environmental safety
Zhang H,Xie Z,Peng Y,Xie A,Fu C,Zheng D,Cai Z,Zhong J,Ming Q,Li M,Lu R,Liu X,Chen J
Wed Mar 01 00:00:00 UTC 2023
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Ecotoxicology and environmental safety
Zhang H,Xie Z,Peng Y,Xie A,Fu C,Zheng D,Cai Z,Zhong J,Ming Q,Li M,Lu R,Liu X,Chen J
Wed Mar 01 00:00:00 UTC 2023
Ring domains are essential for GATOR2-dependent mTORC1 activation.
Molecular cell
Jiang C,Dai X,He S,Zhou H,Fang L,Guo J,Liu S,Zhang T,Pan W,Yu H,Fu T,Li D,Inuzuka H,Wang P,Xiao J,Wei W
Thu Jan 05 00:00:00 UTC 2023
Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases.
Molecular neurodegeneration
Sampognaro PJ,Arya S,Knudsen GM,Gunderson EL,Sandoval-Perez A,Hodul M,Bowles K,Craik CS,Jacobson MP,Kao AW
Tue May 02 00:00:00 UTC 2023
Homoplantaginin attenuates high glucose-induced vascular endothelial cell apoptosis through promoting autophagy via the AMPK/TFEB pathway.
Phytotherapy research : PTR
Fan L,Zhang X,Huang Y,Zhang B,Li W,Shi Q,Lin Y,Wu F
Sat Jul 01 00:00:00 UTC 2023
Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer.
Cancers
Huang Z,Zhu S,Han Z,Li C,Liang J,Wang Y,Zhang S,Zhang J
Wed Jan 25 00:00:00 UTC 2023
Grain-sized moxibustion at Zusanli (ST36) promotes hepatic autophagy in rats with hyperlipidemia by regulating the ULK1 and TFEB expression through the AMPK/mTOR signaling pathway.
Heliyon
Xu Q,Wu H,Zhu H,Lu C,Tao J,Zhou Z,Zhang J
Mon May 01 00:00:00 UTC 2023
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
Translational research : the journal of laboratory and clinical medicine
Zhou J,Lu Y,Lin Y,Li C,Liu J,Jiang Z,Chen K
Tue Aug 01 00:00:00 UTC 2023
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
Translational research : the journal of laboratory and clinical medicine
Zhou J,Lu Y,Lin Y,Li C,Liu J,Jiang Z,Chen K
Tue Aug 01 00:00:00 UTC 2023
De novo missense variants in RRAGC lead to a fatal mTORopathy of early childhood.
Genetics in medicine : official journal of the American College of Medical Genetics
Reijnders MRF,Seibt A,Brugger M,Lamers IJC,Ott T,Klaas O,Horváth J,Rose AMS,Craghill IM,Brunet T,Graf E,Mayerhanser K,Hellebrekers D,Pauck D,Neuen-Jacob E,Rodenburg RJT,Wieczorek D,Klee D,Mayatepek E,Driessen G,Bindermann R,Averdunk L,Lohmeier K,Sinnema M,Stegmann APA,Roepman R,Poulter JA,Distelmaier F
Sat Jul 01 00:00:00 UTC 2023
Doxorubicin induces cardiomyocyte death owing to the accumulation of dysfunctional mitochondria by inhibiting the autophagy fusion process.
Free radical biology & medicine
Toda N,Sato T,Muraoka M,Lin D,Saito M,Li G,Song QC,Yanagisawa T,Yamauchi M
Wed Feb 01 00:00:00 UTC 2023
The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation.
Molecules (Basel, Switzerland)
Liao Y,Wang JY,Pan Y,Zou X,Wang C,Peng Y,Ao YL,Lam MF,Zhang X,Zhang XQ,Shi L,Zhang S
Sat Mar 04 00:00:00 UTC 2023
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
The Science of the total environment
Pei X,Liu D,Li J,Li L,Ding X,Zhang W,Li Z,Xu G,Li C,Li D
Mon Mar 20 00:00:00 UTC 2023
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
The Science of the total environment
Pei X,Liu D,Li J,Li L,Ding X,Zhang W,Li Z,Xu G,Li C,Li D
Mon Mar 20 00:00:00 UTC 2023
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Ecotoxicology and environmental safety
Zhang J,Tang Y,Hu Z,Xu W,Ma Y,Xu P,Xing H,Niu Q
Sun Jan 15 00:00:00 UTC 2023
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Ecotoxicology and environmental safety
Zhang J,Tang Y,Hu Z,Xu W,Ma Y,Xu P,Xing H,Niu Q
Sun Jan 15 00:00:00 UTC 2023
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Ecotoxicology and environmental safety
Zhang J,Tang Y,Hu Z,Xu W,Ma Y,Xu P,Xing H,Niu Q
Sun Jan 15 00:00:00 UTC 2023
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Ecotoxicology and environmental safety
Zhang J,Tang Y,Hu Z,Xu W,Ma Y,Xu P,Xing H,Niu Q
Sun Jan 15 00:00:00 UTC 2023
A racemosin B derivative, C25, suppresses breast cancer growth via lysosomal membrane permeabilization and inhibition of autophagic flux.
Biochemical pharmacology
Xiao X,Chung PED,Xu M,Hu A,Ju Y,Yang X,Song J,Song J,Wang C,Zacksenhaus E,Liu S,He Z,Ben-David Y
Fri Jul 01 00:00:00 UTC 2022
Hyperphosphatemia-induced degradation of transcription factor EB exacerbates vascular calcification.
Biochimica et biophysica acta. Molecular basis of disease
Ishiwata R,Morimoto Y
Tue Mar 01 00:00:00 UTC 2022
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jiang X,Zhang K,Gao C,Ma W,Liu M,Guo X,Bao G,Han B,Hu H,Zhao Z
Thu Dec 01 00:00:00 UTC 2022
Activation of FMS-like tyrosine kinase 3 protects against isoprenaline-induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jiang X,Zhang K,Gao C,Ma W,Liu M,Guo X,Bao G,Han B,Hu H,Zhao Z
Thu Dec 01 00:00:00 UTC 2022
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
Brain research
Zhang Y,Wu Z,Huang Z,Liu Y,Chen X,Zhao X,He H,Deng Y
Tue Mar 01 00:00:00 UTC 2022
Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation.
Heliyon
Ding X,Yang X,Zhao Y,Wang Y,Fei J,Niu Z,Dong X,Wang X,Liu B,Li H,Hao X,Zhao Y
Sat Oct 01 00:00:00 UTC 2022
Vitamin D Attenuates Pain and Cartilage Destruction in OA Animals via Enhancing Autophagic Flux and Attenuating Inflammatory Cell Death.
Immune network
Jhun J,Woo JS,Kwon JY,Na HS,Cho KH,Kim SA,Kim SJ,Moon SJ,Park SH,Cho ML
Mon Aug 01 00:00:00 UTC 2022
TLR4-Mediated Inflammatory Responses Regulate Exercise-Induced Molecular Adaptations in Mouse Skeletal Muscle.
International journal of molecular sciences
Fujiyoshi H,Egawa T,Kurogi E,Yokokawa T,Kido K,Hayashi T
Mon Feb 07 00:00:00 UTC 2022
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Acta neuropathologica
Chen S,Acosta D,Li L,Liang J,Chang Y,Wang C,Fitzgerald J,Morrison C,Goulbourne CN,Nakano Y,Villegas NCH,Venkataraman L,Brown C,Serrano GE,Bell E,Wemlinger T,Wu M,Kokiko-Cochran ON,Popovich P,Flowers XE,Honig LS,Vonsattel JP,Scharre DW,Beach TG,Ma Q,Kuret J,Kõks S,Urano F,Duff KE,Fu H
Sun May 01 00:00:00 UTC 2022
Quercetin protects against palmitate-induced pancreatic β-cell apoptosis by restoring lysosomal function and autophagic flux.
The Journal of nutritional biochemistry
Liu H,Zhou W,Guo L,Zhang H,Guan L,Yan X,Zhai Y,Qiao Y,Wang Z,Zhao J,Lyu K,Li P,Wang H,Peng L
Thu Sep 01 00:00:00 UTC 2022
Up-regulation of NMRK2 mediated by TFE3 fusions is the key for energy metabolism adaption of Xp11.2 translocation renal cell carcinoma.
Cancer letters
Chen Y,Yang L,Lu Y,Liu N,Ma W,Fan H,Hu Q,Han X,Gan W,Li D
Sun Jul 10 00:00:00 UTC 2022
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Stem cell research & therapy
Tan J,Xu T,Gou Y,Wang H,Liang Z,Cao Y,Wang H,Yu Y,Jiao N,Zhang Z
Fri Jul 15 00:00:00 UTC 2022
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Stem cell research & therapy
Tan J,Xu T,Gou Y,Wang H,Liang Z,Cao Y,Wang H,Yu Y,Jiao N,Zhang Z
Fri Jul 15 00:00:00 UTC 2022
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Environmental toxicology
Zhao Y,Mao A,Zhang R,Guan S,Lu J
Tue Mar 01 00:00:00 UTC 2022
Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D.
Cells
Huang P,Cao Q,Xu M,Dong XP
Fri Mar 04 00:00:00 UTC 2022
Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D.
Cells
Huang P,Cao Q,Xu M,Dong XP
Fri Mar 04 00:00:00 UTC 2022
Effect and mechanism of TFEB on pyroptosis in HK-2 cells induced by high glucose.
Biochemical and biophysical research communications
Han N,Wang Z,Luo H,Chi Y,Zhang T,Wang B,Li Y
Sat Jun 25 00:00:00 UTC 2022
Harmol promotes α-synuclein degradation and improves motor impairment in Parkinson's models via regulating autophagy-lysosome pathway.
NPJ Parkinson's disease
Xu J,Ao YL,Huang C,Song X,Zhang G,Cui W,Wang Y,Zhang XQ,Zhang Z
Sat Aug 06 00:00:00 UTC 2022
Harmol promotes α-synuclein degradation and improves motor impairment in Parkinson's models via regulating autophagy-lysosome pathway.
NPJ Parkinson's disease
Xu J,Ao YL,Huang C,Song X,Zhang G,Cui W,Wang Y,Zhang XQ,Zhang Z
Sat Aug 06 00:00:00 UTC 2022
Harmol promotes α-synuclein degradation and improves motor impairment in Parkinson's models via regulating autophagy-lysosome pathway.
NPJ Parkinson's disease
Xu J,Ao YL,Huang C,Song X,Zhang G,Cui W,Wang Y,Zhang XQ,Zhang Z
Sat Aug 06 00:00:00 UTC 2022
Harmol promotes α-synuclein degradation and improves motor impairment in Parkinson's models via regulating autophagy-lysosome pathway.
NPJ Parkinson's disease
Xu J,Ao YL,Huang C,Song X,Zhang G,Cui W,Wang Y,Zhang XQ,Zhang Z
Sat Aug 06 00:00:00 UTC 2022
Aerobic Exercise Alleviates Abnormal Autophagy in Brain Cells of APP/PS1 Mice by Upregulating AdipoR1 Levels.
International journal of molecular sciences
Jian Y,Yuan S,Yang J,Lei Y,Li X,Liu W
Wed Aug 31 00:00:00 UTC 2022
Aerobic Exercise Alleviates Abnormal Autophagy in Brain Cells of APP/PS1 Mice by Upregulating AdipoR1 Levels.
International journal of molecular sciences
Jian Y,Yuan S,Yang J,Lei Y,Li X,Liu W
Wed Aug 31 00:00:00 UTC 2022
Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.
Frontiers in pharmacology
Zhou J,Chen H,Du J,Tai H,Han X,Huang N,Wang X,Gong H,Yang M,Xiao H
Fri Jul 22 00:00:00 UTC 2022
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.
Communications biology
Chen Z,Wu H,Yang J,Li B,Ding J,Cheng S,Bsoul N,Zhang C,Li J,Liu H,Lin D,Gao W
Wed Jun 22 00:00:00 UTC 2022
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.
Communications biology
Chen Z,Wu H,Yang J,Li B,Ding J,Cheng S,Bsoul N,Zhang C,Li J,Liu H,Lin D,Gao W
Wed Jun 22 00:00:00 UTC 2022
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.
Communications biology
Chen Z,Wu H,Yang J,Li B,Ding J,Cheng S,Bsoul N,Zhang C,Li J,Liu H,Lin D,Gao W
Wed Jun 22 00:00:00 UTC 2022
TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.
Journal of hazardous materials
Tang H,Huang H,Wang D,Li P,Tian Z,Li D,Wang S,Ma R,Xia T,Wang A
Sun May 15 00:00:00 UTC 2022
TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.
Journal of hazardous materials
Tang H,Huang H,Wang D,Li P,Tian Z,Li D,Wang S,Ma R,Xia T,Wang A
Sun May 15 00:00:00 UTC 2022
TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.
Journal of hazardous materials
Tang H,Huang H,Wang D,Li P,Tian Z,Li D,Wang S,Ma R,Xia T,Wang A
Sun May 15 00:00:00 UTC 2022
By restoring autophagic flux and improving mitochondrial function, corosolic acid protects against Dox-induced cardiotoxicity.
Cell biology and toxicology
Che Y,Wang Z,Yuan Y,Zhou H,Wu H,Wang S,Tang Q
Wed Jun 01 00:00:00 UTC 2022
By restoring autophagic flux and improving mitochondrial function, corosolic acid protects against Dox-induced cardiotoxicity.
Cell biology and toxicology
Che Y,Wang Z,Yuan Y,Zhou H,Wu H,Wang S,Tang Q
Wed Jun 01 00:00:00 UTC 2022
By restoring autophagic flux and improving mitochondrial function, corosolic acid protects against Dox-induced cardiotoxicity.
Cell biology and toxicology
Che Y,Wang Z,Yuan Y,Zhou H,Wu H,Wang S,Tang Q
Wed Jun 01 00:00:00 UTC 2022
By restoring autophagic flux and improving mitochondrial function, corosolic acid protects against Dox-induced cardiotoxicity.
Cell biology and toxicology
Che Y,Wang Z,Yuan Y,Zhou H,Wu H,Wang S,Tang Q
Wed Jun 01 00:00:00 UTC 2022
Elabela ameliorates doxorubicin-induced cardiotoxicity by promoting autophagic flux through TFEB pathway.
Pharmacological research
Chen D,Yu W,Zhong C,Hong Q,Huang G,Que D,Wang Y,Yang Y,Rui B,Zhuang Z,Liang M,Ye Z,Yan X,Lv J,Zhang R,Yan J,Yang P
Fri Apr 01 00:00:00 UTC 2022
Berberine-mediated REDD1 down-regulation ameliorates senescence of retinal pigment epithelium by interrupting the ROS-DDR positive feedback loop.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen Q,Xin G,Li S,Dong Y,Yu X,Wan C,Wei Z,Zhu Y,Zhang K,Wang Y,Li F,Zhang C,Wen E,Li Y,Niu H,Huang W
Thu Sep 01 00:00:00 UTC 2022
Activation of Transcription Factor EB Is Associated With Adipose Tissue Lipolysis in Dairy Cows With Subclinical Ketosis.
Frontiers in veterinary science
Yu H,Gao X,Loor JJ,Jiang Q,Fang Z,Hao X,Shi Z,Fan M,Chen M,Li X,Liu G,Wang Z,Li X,Du X
Sat Feb 26 00:00:00 UTC 2022
Metformin Alleviates Epirubicin-Induced Endothelial Impairment by Restoring Mitochondrial Homeostasis.
International journal of molecular sciences
Sun Q,Jia H,Cheng S,Wang Y,Wang J
Sun Dec 25 00:00:00 UTC 2022
Tubastatin A Improves Post-Resuscitation Myocardial Dysfunction by Inhibiting NLRP3-Mediated Pyroptosis Through Enhancing Transcription Factor EB Signaling.
Journal of the American Heart Association
Xu J,Zhao X,Jiang X,He L,Wu X,Wang J,Chen Q,Li Y,Zhang M
Tue Apr 05 00:00:00 UTC 2022
Tubastatin A Improves Post-Resuscitation Myocardial Dysfunction by Inhibiting NLRP3-Mediated Pyroptosis Through Enhancing Transcription Factor EB Signaling.
Journal of the American Heart Association
Xu J,Zhao X,Jiang X,He L,Wu X,Wang J,Chen Q,Li Y,Zhang M
Tue Apr 05 00:00:00 UTC 2022
Restoration of Autophagic Flux Improves Endothelial Function in Diabetes Through Lowering Mitochondrial ROS-Mediated eNOS Monomerization.
Diabetes
Zhao L,Zhang CL,He L,Chen Q,Liu L,Kang L,Liu J,Luo JY,Gou L,Qu D,Song W,Lau CW,Ko H,Mok VCT,Tian XY,Wang L,Huang Y
Sun May 01 00:00:00 UTC 2022
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Clinical and experimental pharmacology & physiology
Wang P,Li CG,Zhou X,Ding S
Tue Feb 01 00:00:00 UTC 2022
Bioengineered microglia-targeted exosomes facilitate Aβ clearance via enhancing activity of microglial lysosome for promoting cognitive recovery in Alzheimer's disease.
Biomaterials advances
Hao Y,Su C,Liu X,Sui H,Shi Y,Zhao L
Sun May 01 00:00:00 UTC 2022
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions.
Autophagy
Zhou Z,Wang H,Zhang X,Song M,Yao S,Jiang P,Liu D,Wang Z,Lv H,Li R,Hong Y,Dai J,Hu Y,Zhao G
Sat Oct 01 00:00:00 UTC 2022
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions.
Autophagy
Zhou Z,Wang H,Zhang X,Song M,Yao S,Jiang P,Liu D,Wang Z,Lv H,Li R,Hong Y,Dai J,Hu Y,Zhao G
Sat Oct 01 00:00:00 UTC 2022
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions.
Autophagy
Zhou Z,Wang H,Zhang X,Song M,Yao S,Jiang P,Liu D,Wang Z,Lv H,Li R,Hong Y,Dai J,Hu Y,Zhao G
Sat Oct 01 00:00:00 UTC 2022
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions.
Autophagy
Zhou Z,Wang H,Zhang X,Song M,Yao S,Jiang P,Liu D,Wang Z,Lv H,Li R,Hong Y,Dai J,Hu Y,Zhao G
Sat Oct 01 00:00:00 UTC 2022
Phillygenin ameliorates nonalcoholic fatty liver disease via TFEB-mediated lysosome biogenesis and lipophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou W,Yan X,Zhai Y,Liu H,Guan L,Qiao Y,Jiang J,Peng L
Mon Aug 01 00:00:00 UTC 2022
Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Deng L,Liu W,Xu Q,Guo R,Zhang D,Ni J,Li L,Cai X,Fan G,Zhao Y
Sat Jan 01 00:00:00 UTC 2022
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2.
Acta pharmacologica Sinica
Yang CB,Liu J,Tong BC,Wang ZY,Zhu Z,Su CF,Sreenivasmurthy SG,Wu JX,Iyaswamy A,Krishnamoorthi S,Huang SY,Cheung KH,Song JX,Tan JQ,Lu JH,Li M
Sun May 01 00:00:00 UTC 2022
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2.
Acta pharmacologica Sinica
Yang CB,Liu J,Tong BC,Wang ZY,Zhu Z,Su CF,Sreenivasmurthy SG,Wu JX,Iyaswamy A,Krishnamoorthi S,Huang SY,Cheung KH,Song JX,Tan JQ,Lu JH,Li M
Sun May 01 00:00:00 UTC 2022
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity.
Molecular cell
Zhang Z,Chen C,Yang F,Zeng YX,Sun P,Liu P,Li X
Thu Aug 04 00:00:00 UTC 2022
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity.
Molecular cell
Zhang Z,Chen C,Yang F,Zeng YX,Sun P,Liu P,Li X
Thu Aug 04 00:00:00 UTC 2022
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity.
Molecular cell
Zhang Z,Chen C,Yang F,Zeng YX,Sun P,Liu P,Li X
Thu Aug 04 00:00:00 UTC 2022
Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat.
eLife
Wang M,Qi Y,Cao Y,Zhang X,Wang Y,Liu Q,Zhang J,Zhou G,Ai Y,Wei S,Wang L,Liu G,Lian Z,Han H
Tue Jun 28 00:00:00 UTC 2022
TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading.
Molecular psychiatry
Xu Y,Du S,Marsh JA,Horie K,Sato C,Ballabio A,Karch CM,Holtzman DM,Zheng H
Fri Oct 01 00:00:00 UTC 2021
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
Autophagy
Kataura T,Tashiro E,Nishikawa S,Shibahara K,Muraoka Y,Miura M,Sakai S,Katoh N,Totsuka M,Onodera M,Shin-Ya K,Miyamoto K,Sasazawa Y,Hattori N,Saiki S,Imoto M
Sun Aug 01 00:00:00 UTC 2021
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Cell death and differentiation
Chen X,Guan Y,Zhang Y,Jia Y,Li W,Guo C,Li Y,Wang X,Shi Y,Wang Q,Zhu F,Li Y,Zhang L
Thu Apr 01 00:00:00 UTC 2021
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Cell death and differentiation
Chen X,Guan Y,Zhang Y,Jia Y,Li W,Guo C,Li Y,Wang X,Shi Y,Wang Q,Zhu F,Li Y,Zhang L
Thu Apr 01 00:00:00 UTC 2021
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Cell death and differentiation
Chen X,Guan Y,Zhang Y,Jia Y,Li W,Guo C,Li Y,Wang X,Shi Y,Wang Q,Zhu F,Li Y,Zhang L
Thu Apr 01 00:00:00 UTC 2021
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Cell death and differentiation
Chen X,Guan Y,Zhang Y,Jia Y,Li W,Guo C,Li Y,Wang X,Shi Y,Wang Q,Zhu F,Li Y,Zhang L
Thu Apr 01 00:00:00 UTC 2021
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Cell death and differentiation
Chen X,Guan Y,Zhang Y,Jia Y,Li W,Guo C,Li Y,Wang X,Shi Y,Wang Q,Zhu F,Li Y,Zhang L
Thu Apr 01 00:00:00 UTC 2021
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Cell death and differentiation
Chen X,Guan Y,Zhang Y,Jia Y,Li W,Guo C,Li Y,Wang X,Shi Y,Wang Q,Zhu F,Li Y,Zhang L
Thu Apr 01 00:00:00 UTC 2021
YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.
The Journal of clinical investigation
Ikeda S,Nah J,Shirakabe A,Zhai P,Oka SI,Sciarretta S,Guan KL,Shimokawa H,Sadoshima J
Mon Mar 01 00:00:00 UTC 2021
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
Autophagy
Zhang X,Wei M,Fan J,Yan W,Zha X,Song H,Wan R,Yin Y,Wang W
Tue Jun 01 00:00:00 UTC 2021
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
Autophagy
Zhang X,Wei M,Fan J,Yan W,Zha X,Song H,Wan R,Yin Y,Wang W
Tue Jun 01 00:00:00 UTC 2021
Transcription factor EB (TFEB)-mediated autophagy protects bovine mammary epithelial cells against H2O2-induced oxidative damage in vitro.
Journal of animal science and biotechnology
Sun X,Chang R,Tang Y,Luo S,Jiang C,Jia H,Xu Q,Dong Z,Liang Y,Loor JJ,Xu C
Tue Mar 09 00:00:00 UTC 2021
Transcription factor EB (TFEB)-mediated autophagy protects bovine mammary epithelial cells against H2O2-induced oxidative damage in vitro.
Journal of animal science and biotechnology
Sun X,Chang R,Tang Y,Luo S,Jiang C,Jia H,Xu Q,Dong Z,Liang Y,Loor JJ,Xu C
Tue Mar 09 00:00:00 UTC 2021
Positive regulation of TFEB and mitophagy by PGC-1α to alleviate LPS-induced acute lung injury in rats.
Biochemical and biophysical research communications
Liu W,Li Y,Bo L,Li C,Jin F
Fri Nov 05 00:00:00 UTC 2021
Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang B,Cao C,Han D,Bai J,Guo J,Guo Q,Li D,Zhang J,Zhang Z,Wang Y,Tang J,Shen D,Zhang J
Fri Oct 01 00:00:00 UTC 2021
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Journal of neuroinflammation
Chen J,Mao K,Yu H,Wen Y,She H,Zhang H,Liu L,Li M,Li W,Zou F
Mon Dec 20 00:00:00 UTC 2021
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Journal of neuroinflammation
Chen J,Mao K,Yu H,Wen Y,She H,Zhang H,Liu L,Li M,Li W,Zou F
Mon Dec 20 00:00:00 UTC 2021
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Journal of neuroinflammation
Chen J,Mao K,Yu H,Wen Y,She H,Zhang H,Liu L,Li M,Li W,Zou F
Mon Dec 20 00:00:00 UTC 2021
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Journal of neuroinflammation
Chen J,Mao K,Yu H,Wen Y,She H,Zhang H,Liu L,Li M,Li W,Zou F
Mon Dec 20 00:00:00 UTC 2021
TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells.
The Biochemical journal
Relic B,Deroyer C,Malaise O,Plener Z,Gillet P,de Seny D,Malaise MG
Fri Aug 27 00:00:00 UTC 2021
Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy.
Investigative ophthalmology & visual science
Shyam R,Ogando DG,Choi M,Liton PB,Bonanno JA
Thu Sep 02 00:00:00 UTC 2021
Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Xie C,Shi Y,Chen Z,Zhou X,Luo P,Hong C,Tian N,Wu Y,Zhou Y,Lin Y,Dou H,Wu A,Huang Q,Zhang X,Wang X
Tue Feb 01 00:00:00 UTC 2022
Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Xie C,Shi Y,Chen Z,Zhou X,Luo P,Hong C,Tian N,Wu Y,Zhou Y,Lin Y,Dou H,Wu A,Huang Q,Zhang X,Wang X
Tue Feb 01 00:00:00 UTC 2022
PMEPA1 and NEDD4 control the proton production of osteoclasts by regulating vesicular trafficking.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Hirata H,Xu X,Nishioka K,Matsuhisa F,Kitajima S,Kukita T,Murayama M,Urano Y,Miyamoto H,Mawatari M,Kukita A
Mon Feb 01 00:00:00 UTC 2021
Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells.
Chemico-biological interactions
Wang S,Guo R,Su Y,Yang C,Guo Y,Tan C,Zhao B
Thu Feb 25 00:00:00 UTC 2021
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Journal of food science
Lu J,Lu J,Bu X,Li Y,Ge G,Guan S
Wed Dec 01 00:00:00 UTC 2021
20-Deoxyingenol alleviates osteoarthritis by activating TFEB in chondrocytes.
Pharmacological research
Gu M,Jin J,Ren C,Chen X,Pan Z,Wu Y,Tian N,Sun L,Wu A,Gao W,Zhou Y,Lin Z,Zhang X
Mon Mar 01 00:00:00 UTC 2021
20-Deoxyingenol alleviates osteoarthritis by activating TFEB in chondrocytes.
Pharmacological research
Gu M,Jin J,Ren C,Chen X,Pan Z,Wu Y,Tian N,Sun L,Wu A,Gao W,Zhou Y,Lin Z,Zhang X
Mon Mar 01 00:00:00 UTC 2021
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
Life (Basel, Switzerland)
Wu Z,Zhang Y,Liu Y,Chen X,Huang Z,Zhao X,He H,Deng Y
Fri Sep 10 00:00:00 UTC 2021
Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.
Life (Basel, Switzerland)
Wu Z,Zhang Y,Liu Y,Chen X,Huang Z,Zhao X,He H,Deng Y
Fri Sep 10 00:00:00 UTC 2021
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Cell death & disease
Han Y,Xiong S,Zhao H,Yang S,Yang M,Zhu X,Jiang N,Xiong X,Gao P,Wei L,Xiao Y,Sun L
Sat Oct 30 00:00:00 UTC 2021
Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway.
Cell death & disease
Fang S,Wan X,Zou X,Sun S,Hao X,Liang C,Zhang Z,Zhang F,Sun B,Li H,Yu B
Mon Jan 18 00:00:00 UTC 2021
Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway.
Cell death & disease
Fang S,Wan X,Zou X,Sun S,Hao X,Liang C,Zhang Z,Zhang F,Sun B,Li H,Yu B
Mon Jan 18 00:00:00 UTC 2021
Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease.
Pharmacological research
Zhang H,Lu J,Liu H,Guan L,Xu S,Wang Z,Qiu Y,Liu H,Peng L,Men X
Wed Dec 01 00:00:00 UTC 2021
Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease.
Pharmacological research
Zhang H,Lu J,Liu H,Guan L,Xu S,Wang Z,Qiu Y,Liu H,Peng L,Men X
Wed Dec 01 00:00:00 UTC 2021
Lysosomal nitric oxide determines transition from autophagy to ferroptosis after exposure to plasma-activated Ringer's lactate.
Redox biology
Jiang L,Zheng H,Lyu Q,Hayashi S,Sato K,Sekido Y,Nakamura K,Tanaka H,Ishikawa K,Kajiyama H,Mizuno M,Hori M,Toyokuni S
Thu Jul 01 00:00:00 UTC 2021
Quercetin alleviates Cadmium-induced autophagy inhibition via TFEB-dependent lysosomal restoration in primary proximal tubular cells.
Ecotoxicology and environmental safety
Zhao Y,Li ZF,Zhang D,Wang ZY,Wang L
Fri Jan 15 00:00:00 UTC 2021
Quercetin alleviates Cadmium-induced autophagy inhibition via TFEB-dependent lysosomal restoration in primary proximal tubular cells.
Ecotoxicology and environmental safety
Zhao Y,Li ZF,Zhang D,Wang ZY,Wang L
Fri Jan 15 00:00:00 UTC 2021
TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis.
Autophagy
Suzuki N,Johmura Y,Wang TW,Migita T,Wu W,Noguchi R,Yamaguchi K,Furukawa Y,Nakamura S,Miyoshi I,Yoshimori T,Ohta T,Nakanishi M
Mon Nov 01 00:00:00 UTC 2021
Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling.
Phytotherapy research : PTR
Li D,Cui Y,Wang X,Liu F,Li X
Mon Mar 01 00:00:00 UTC 2021
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
Cell death discovery
Liu W,Wang Y,Xie Y,Dai T,Fan M,Li C,Zou Y
Sat Jun 05 00:00:00 UTC 2021
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
Cell death discovery
Liu W,Wang Y,Xie Y,Dai T,Fan M,Li C,Zou Y
Sat Jun 05 00:00:00 UTC 2021
Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging.
Oxidative medicine and cellular longevity
Zhang S,Zhang Y,Zhang X,Luo C,Cao Y,Ji D,Yan W,Xue K,Chai J,Dai H,Wang W
Mon Sep 21 00:00:00 UTC 2020
Activation of α7nACh receptor protects against acute pancreatitis through enhancing TFEB-regulated autophagy.
Biochimica et biophysica acta. Molecular basis of disease
Li B,Wu J,Bao J,Han X,Shen S,Ye X,Dai J,Wu Z,Niu M,He Y,Ni J,Wen L,Wang X,Hu G
Tue Dec 01 00:00:00 UTC 2020
Activation of α7nACh receptor protects against acute pancreatitis through enhancing TFEB-regulated autophagy.
Biochimica et biophysica acta. Molecular basis of disease
Li B,Wu J,Bao J,Han X,Shen S,Ye X,Dai J,Wu Z,Niu M,He Y,Ni J,Wen L,Wang X,Hu G
Tue Dec 01 00:00:00 UTC 2020
Blue light-emitting diode irradiation promotes transcription factor EB-mediated lysosome biogenesis and lysosomal cell death in murine photoreceptor-derived cells.
Biochemical and biophysical research communications
Otsu W,Ishida K,Nakamura S,Shimazawa M,Tsusaki H,Hara H
Thu May 28 00:00:00 UTC 2020
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Molecular cancer research : MCR
Li S,Liu F,Xu L,Li C,Yang X,Guo B,Gu J,Wang L
Sun Nov 01 00:00:00 UTC 2020
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Molecular cancer research : MCR
Li S,Liu F,Xu L,Li C,Yang X,Guo B,Gu J,Wang L
Sun Nov 01 00:00:00 UTC 2020
A Self-Assembled α-Synuclein Nanoscavenger for Parkinson's Disease.
ACS nano
Liu J,Liu C,Zhang J,Zhang Y,Liu K,Song JX,Sreenivasmurthy SG,Wang Z,Shi Y,Chu C,Zhang Y,Wu C,Deng X,Liu X,Song J,Zhuang R,Huang S,Zhang P,Li M,Wen L,Zhang YW,Liu G
Tue Feb 25 00:00:00 UTC 2020
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.
Nature communications
Sun X,Zhou Y,Zhang R,Wang Z,Xu M,Zhang D,Huang J,Luo F,Li F,Ni Z,Zhou S,Chen H,Chen S,Chen L,Du X,Chen B,Huang H,Liu P,Yin L,Qiu J,Chen D,Deng C,Xie Y,Luo L,Chen L
Fri Jan 24 00:00:00 UTC 2020
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.
Nature communications
Sun X,Zhou Y,Zhang R,Wang Z,Xu M,Zhang D,Huang J,Luo F,Li F,Ni Z,Zhou S,Chen H,Chen S,Chen L,Du X,Chen B,Huang H,Liu P,Yin L,Qiu J,Chen D,Deng C,Xie Y,Luo L,Chen L
Fri Jan 24 00:00:00 UTC 2020
HGF protected against diabetic nephropathy via autophagy-lysosome pathway in podocyte by modulating PI3K/Akt-GSK3β-TFEB axis.
Cellular signalling
Hou B,Li Y,Li X,Zhang C,Zhao Z,Chen Q,Zhang N,Li H
Sun Nov 01 00:00:00 UTC 2020
TFEB-NF-κB inflammatory signaling axis: a novel therapeutic pathway of Dihydrotanshinone I in doxorubicin-induced cardiotoxicity.
Journal of experimental & clinical cancer research : CR
Wang X,Wang Q,Li W,Zhang Q,Jiang Y,Guo D,Sun X,Lu W,Li C,Wang Y
Sun May 24 00:00:00 UTC 2020
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
Frontiers in pharmacology
Xu Q,Fan Y,Loor JJ,Liang Y,Sun X,Jia H,Zhao C,Xu C
Thu Dec 31 00:00:00 UTC 2020
Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.
Aging cell
Mao K,Chen J,Yu H,Li H,Ren Y,Wu X,Wen Y,Zou F,Li W
Mon Jun 01 00:00:00 UTC 2020
Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.
Aging cell
Mao K,Chen J,Yu H,Li H,Ren Y,Wu X,Wen Y,Zou F,Li W
Mon Jun 01 00:00:00 UTC 2020
LSD1 negatively regulates autophagy in myoblast cells by driving PTEN degradation.
Biochemical and biophysical research communications
Shi YX,He YJ,Zhou Y,Li HK,Yang D,Li RY,Deng ZL,Gao YF
Wed Feb 19 00:00:00 UTC 2020
NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux.
Basic research in cardiology
Zhang YJ,Zhang M,Zhao X,Shi K,Ye M,Tian J,Guan S,Ying W,Qu X
Mon Aug 10 00:00:00 UTC 2020
NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux.
Basic research in cardiology
Zhang YJ,Zhang M,Zhao X,Shi K,Ye M,Tian J,Guan S,Ying W,Qu X
Mon Aug 10 00:00:00 UTC 2020
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
Nanoscale research letters
Pang C,Song C,Li Y,Wang Q,Zhu X,Wu J,Tian Y,Fan H,Hu J,Li C,Wang B,Li X,Liu W,Fan L
Wed Jul 08 00:00:00 UTC 2020
Remote ischemic postconditioning attenuates damage in rats with chronic cerebral ischemia by upregulating the autophagolysosome pathway via the activation of TFEB.
Experimental and molecular pathology
Li Z,Cui X,Lv H,Liu J,Di W,Jiang F,Liu Y,Cheng X
Sat Aug 01 00:00:00 UTC 2020
Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.
Autophagy
Unno R,Kawabata T,Taguchi K,Sugino T,Hamamoto S,Ando R,Okada A,Kohri K,Yoshimori T,Yasui T
Wed Apr 01 00:00:00 UTC 2020
The neuroprotective effects of activated α7 nicotinic acetylcholine receptor against mutant copper-zinc superoxide dismutase 1-mediated toxicity.
Scientific reports
Ito T,Inden M,Ueda T,Asaka Y,Kurita H,Hozumi I
Thu Dec 17 00:00:00 UTC 2020
The neuroprotective effects of activated α7 nicotinic acetylcholine receptor against mutant copper-zinc superoxide dismutase 1-mediated toxicity.
Scientific reports
Ito T,Inden M,Ueda T,Asaka Y,Kurita H,Hozumi I
Thu Dec 17 00:00:00 UTC 2020
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
Cells
He X,Chen S,Li C,Ban J,Wei Y,He Y,Liu F,Chen Y,Chen J
Sat Jan 04 00:00:00 UTC 2020
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
Cells
He X,Chen S,Li C,Ban J,Wei Y,He Y,Liu F,Chen Y,Chen J
Sat Jan 04 00:00:00 UTC 2020
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
American journal of physiology. Renal physiology
Liu S,Yang Y,Gao H,Zhou N,Wang P,Zhang Y,Zhang A,Jia Z,Huang S
Wed Apr 01 00:00:00 UTC 2020
3-Acetyldeoxynivalenol induces lysosomal membrane permeabilization-mediated apoptosis and inhibits autophagic flux in macrophages.
Environmental pollution (Barking, Essex : 1987)
Liu N,Yang Y,Chen J,Jia H,Zhang Y,Jiang D,Wu G,Wu Z
Thu Oct 01 00:00:00 UTC 2020
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Cell death & disease
Ma WQ,Sun XJ,Zhu Y,Liu NF
Tue Nov 17 00:00:00 UTC 2020
Irisin reverses insulin resistance in C2C12 cells via the p38-MAPK-PGC-1α pathway.
Peptides
Ye X,Shen Y,Ni C,Ye J,Xin Y,Zhang W,Ren Y
Sun Sep 01 00:00:00 UTC 2019
NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer.
Journal of experimental & clinical cancer research : CR
Song X,Liu L,Chang M,Geng X,Wang X,Wang W,Chen TC,Xie L,Song X
Fri Jun 07 00:00:00 UTC 2019
Loss of spatacsin impairs cholesterol trafficking and calcium homeostasis.
Communications biology
Boutry M,Pierga A,Matusiak R,Branchu J,Houllegatte M,Ibrahim Y,Balse E,El Hachimi KH,Brice A,Stevanin G,Darios F
Mon Apr 27 00:00:00 UTC 2020
TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.
Neuroscience
Yamamoto F,Taniguchi K,Mamada N,Tamaoka A,Kametani F,Lakshmana MK,Araki W
Fri Mar 15 00:00:00 UTC 2019
TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.
Neuroscience
Yamamoto F,Taniguchi K,Mamada N,Tamaoka A,Kametani F,Lakshmana MK,Araki W
Fri Mar 15 00:00:00 UTC 2019
TFEB Probably Involved in Midazolam-Disturbed Lysosomal Homeostasis and Its Induced β-Amyloid Accumulation.
Frontiers in human neuroscience
Cheng D,Tan Q,Zhu Q,Zhang J,Han X,Fang P,Jin W,Liu X
Wed Sep 30 00:00:00 UTC 2020
Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.
International journal of molecular medicine
Kang Y,Li Y,Zhang T,Chi Y,Liu M
Thu Aug 01 00:00:00 UTC 2019
Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.
International journal of molecular medicine
Kang Y,Li Y,Zhang T,Chi Y,Liu M
Thu Aug 01 00:00:00 UTC 2019
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Journal of lipid research
Li Y,Yang P,Zhao L,Chen Y,Zhang X,Zeng S,Wei L,Varghese Z,Moorhead JF,Chen Y,Ruan XZ
Mon Apr 01 00:00:00 UTC 2019
Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress.
Redox biology
Chakraborty D,Felzen V,Hiebel C,Stürner E,Perumal N,Manicam C,Sehn E,Grus F,Wolfrum U,Behl C
Sat Jun 01 00:00:00 UTC 2019
Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1.
Cancers
Wang X,Li C,Wang Q,Li W,Guo D,Zhang X,Shao M,Chen X,Ma L,Zhang Q,Wang W,Wang Y
Fri Jun 28 00:00:00 UTC 2019
TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells.
Journal of experimental & clinical cancer research : CR
He R,Wang M,Zhao C,Shen M,Yu Y,He L,Zhao Y,Chen H,Shi X,Zhou M,Pan S,Liu Y,Guo X,Li X,Qin R
Tue Aug 06 00:00:00 UTC 2019
Overexpression of transcription factor EB regulates mitochondrial autophagy to protect lipopolysaccharide-induced acute lung injury.
Chinese medical journal
Liu W,Li CC,Lu X,Bo LY,Jin FG
Wed Jun 05 00:00:00 UTC 2019
Overexpression of transcription factor EB regulates mitochondrial autophagy to protect lipopolysaccharide-induced acute lung injury.
Chinese medical journal
Liu W,Li CC,Lu X,Bo LY,Jin FG
Wed Jun 05 00:00:00 UTC 2019
mTORC1 inhibition attenuates necroptosis through RIP1 inhibition-mediated TFEB activation.
Biochimica et biophysica acta. Molecular basis of disease
Abe K,Yano T,Tanno M,Miki T,Kuno A,Sato T,Kouzu H,Nakata K,Ohwada W,Kimura Y,Sugawara H,Shibata S,Igaki Y,Ino S,Miura T
Sun Dec 01 00:00:00 UTC 2019
mTORC1 inhibition attenuates necroptosis through RIP1 inhibition-mediated TFEB activation.
Biochimica et biophysica acta. Molecular basis of disease
Abe K,Yano T,Tanno M,Miki T,Kuno A,Sato T,Kouzu H,Nakata K,Ohwada W,Kimura Y,Sugawara H,Shibata S,Igaki Y,Ino S,Miura T
Sun Dec 01 00:00:00 UTC 2019
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
Nutrition & metabolism
Xue M,Liang H,Ji X,Liu Y,Ge Y,Hou L,Sun T
Tue Apr 12 00:00:00 UTC 2022
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency.
Autophagy
Lotfi P,Tse DY,Di Ronza A,Seymour ML,Martano G,Cooper JD,Pereira FA,Passafaro M,Wu SM,Sardiello M
Fri Oct 11 00:00:00 UTC 2019
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency.
Autophagy
Lotfi P,Tse DY,Di Ronza A,Seymour ML,Martano G,Cooper JD,Pereira FA,Passafaro M,Wu SM,Sardiello M
Fri Oct 11 00:00:00 UTC 2019
A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration.
Frontiers in aging neuroscience
Jin MM,Wang F,Qi D,Liu WW,Gu C,Mao CJ,Yang YP,Zhao Z,Hu LF,Liu CF
Wed Sep 30 00:00:00 UTC 2020
A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration.
Frontiers in aging neuroscience
Jin MM,Wang F,Qi D,Liu WW,Gu C,Mao CJ,Yang YP,Zhao Z,Hu LF,Liu CF
Wed Sep 30 00:00:00 UTC 2020
Autophagic Modulation by Trehalose Reduces Accumulation of TDP-43 in a Cell Model of Amyotrophic Lateral Sclerosis via TFEB Activation.
Neurotoxicity research
Wang Y,Liu FT,Wang YX,Guan RY,Chen C,Li DK,Bu LL,Song J,Yang YJ,Dong Y,Chen Y,Wang J
Sun Jul 01 00:00:00 UTC 2018
Autophagic Modulation by Trehalose Reduces Accumulation of TDP-43 in a Cell Model of Amyotrophic Lateral Sclerosis via TFEB Activation.
Neurotoxicity research
Wang Y,Liu FT,Wang YX,Guan RY,Chen C,Li DK,Bu LL,Song J,Yang YJ,Dong Y,Chen Y,Wang J
Sun Jul 01 00:00:00 UTC 2018
TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation.
Cell death & disease
Zheng G,Zhan Y,Li X,Pan Z,Zheng F,Zhang Z,Zhou Y,Wu Y,Wang X,Gao W,Xu H,Tian N,Zhang X
Tue Aug 28 00:00:00 UTC 2018
TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation.
Cell death & disease
Zheng G,Zhan Y,Li X,Pan Z,Zheng F,Zhang Z,Zhou Y,Wu Y,Wang X,Gao W,Xu H,Tian N,Zhang X
Tue Aug 28 00:00:00 UTC 2018
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Toxicological sciences : an official journal of the Society of Toxicology
Ren Y,Chen J,Wu X,Gui C,Mao K,Zou F,Li W
Sat Sep 01 00:00:00 UTC 2018
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Toxicological sciences : an official journal of the Society of Toxicology
Ren Y,Chen J,Wu X,Gui C,Mao K,Zou F,Li W
Sat Sep 01 00:00:00 UTC 2018
Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy.
Free radical biology & medicine
Shi L,Ito F,Wang Y,Okazaki Y,Tanaka H,Mizuno M,Hori M,Hirayama T,Nagasawa H,Richardson DR,Toyokuni S
Sat Jul 01 00:00:00 UTC 2017
Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy.
Free radical biology & medicine
Shi L,Ito F,Wang Y,Okazaki Y,Tanaka H,Mizuno M,Hori M,Hirayama T,Nagasawa H,Richardson DR,Toyokuni S
Sat Jul 01 00:00:00 UTC 2017
Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells.
International immunology
Kobayashi T,Tsutsui H,Shimabukuro-Demoto S,Yoshida-Sugitani R,Karyu H,Furuyama-Tanaka K,Ohshima D,Kato N,Okamura T,Toyama-Sorimachi N
Sun Dec 31 00:00:00 UTC 2017
Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells.
International immunology
Kobayashi T,Tsutsui H,Shimabukuro-Demoto S,Yoshida-Sugitani R,Karyu H,Furuyama-Tanaka K,Ohshima D,Kato N,Okamura T,Toyama-Sorimachi N
Sun Dec 31 00:00:00 UTC 2017
Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome.
PloS one
Yang Y,Qin M,Bao P,Xu W,Xu J
Mon Sep 25 00:00:00 UTC 2017
Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome.
PloS one
Yang Y,Qin M,Bao P,Xu W,Xu J
Mon Sep 25 00:00:00 UTC 2017
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.
Nature communications
Palmieri M,Pal R,Nelvagal HR,Lotfi P,Stinnett GR,Seymour ML,Chaudhury A,Bajaj L,Bondar VV,Bremner L,Saleem U,Tse DY,Sanagasetti D,Wu SM,Neilson JR,Pereira FA,Pautler RG,Rodney GG,Cooper JD,Sardiello M
Mon Feb 06 00:00:00 UTC 2017
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.
Nature communications
Palmieri M,Pal R,Nelvagal HR,Lotfi P,Stinnett GR,Seymour ML,Chaudhury A,Bajaj L,Bondar VV,Bremner L,Saleem U,Tse DY,Sanagasetti D,Wu SM,Neilson JR,Pereira FA,Pautler RG,Rodney GG,Cooper JD,Sardiello M
Mon Feb 06 00:00:00 UTC 2017
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition.
Autophagy
Song JX,Sun YR,Peluso I,Zeng Y,Yu X,Lu JH,Xu Z,Wang MZ,Liu LF,Huang YY,Chen LL,Durairajan SS,Zhang HJ,Zhou B,Zhang HQ,Lu A,Ballabio A,Medina DL,Guo Z,Li M
Tue Aug 02 00:00:00 UTC 2016
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition.
Autophagy
Song JX,Sun YR,Peluso I,Zeng Y,Yu X,Lu JH,Xu Z,Wang MZ,Liu LF,Huang YY,Chen LL,Durairajan SS,Zhang HJ,Zhou B,Zhang HQ,Lu A,Ballabio A,Medina DL,Guo Z,Li M
Tue Aug 02 00:00:00 UTC 2016
Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.
Journal of dental research
Wang HS,Pei F,Chen Z,Zhang L
Wed Jun 01 00:00:00 UTC 2016
Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.
Journal of dental research
Wang HS,Pei F,Chen Z,Zhang L
Wed Jun 01 00:00:00 UTC 2016
MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.
American journal of physiology. Lung cellular and molecular physiology
Ahuja S,Knudsen L,Chillappagari S,Henneke I,Ruppert C,Korfei M,Gochuico BR,Bellusci S,Seeger W,Ochs M,Guenther A,Mahavadi P
Tue Mar 15 00:00:00 UTC 2016
MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.
American journal of physiology. Lung cellular and molecular physiology
Ahuja S,Knudsen L,Chillappagari S,Henneke I,Ruppert C,Korfei M,Gochuico BR,Bellusci S,Seeger W,Ochs M,Guenther A,Mahavadi P
Tue Mar 15 00:00:00 UTC 2016
