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OriGene
TGFB1I1 Polyclonal Antibody
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FIGURE: 1 / 2
TGFB1I1 Antibody (TA890151) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TGFB1I1 (RC220280, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-TGFB. Positive lysates LY402475 (100 µg) and LC402475 (20 µg) can be purchased separately from OriGene.
Product Details
TA890151
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein of human TGFB1I1
Conjugate
Form
Liquid
Concentration
2.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Androgen receptor coactivator 55 kDa protein; androgen receptor coactivator ARA55; Androgen receptor-associated protein of 55 kDa; Hic-5; Hydrogen peroxide-inducible clone 5 protein; hydrogen peroxide-inducible clone-5; TGF beta-stimulated clone 5; Transforming growth factor beta-1-induced transcript 1 protein; TSC-5
Gene Aliases: ARA55; HIC-5; HIC5; TGFB1I1; TSC-5
UniProt ID: (Human) O43294, (Mouse) Q62219
Entrez Gene ID: (Human) 7041, (Mouse) 21804
response to heat
positive regulation of epithelial to mesenchymal transition
Wnt signaling pathway
morphogenesis of embryonic epithelium
cell differentiation
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
epithelial cell differentiation
cell fate commitment
negative regulation of fat cell differentiation
positive regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell adhesion
negative regulation of cell proliferation
androgen receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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