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Immunogen sequence: MAALGVQSIN WQTAFNRQAH HTDKFSSQEL ILRRGQNFQV LMIMNKGLGS NERLEFIVST GPYPSESAMT KAVFPLSNGS SGGWSAVLQA SNGNTLTISI SSPASAPIGR YTMALQIFSQ GGISSVKLGT FILLFNPWLN VDSVFMGNHA EREEYVQEDA GIIFVGSTNR IGMIGWNFGQ; Positive Samples: BT-474, A-549, U-87MG
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E polypeptide; E polypeptide, protein-glutamine-gamma-glutamyltransferase; MGC126249; MGC126250; Protein-glutamine gamma-glutamyltransferase E; protein-glutamine-gamma-glutamyltransferase; TG(E); TGase E; TGase TGase-3; TGase-3; Transglutaminase E; Transglutaminase-3
Gene Aliases: AI893889; TG E; TG(E); TGase E; TGase-3; Tgase3; TGE; TGM3
UniProt ID: (Human) Q08188, (Mouse) Q08189
Entrez Gene ID: (Human) 7053, (Mouse) 21818
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