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Product Details
12909-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
THADA Fusion Protein Ag3881 (59-400 aa encoded by BC025773)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TSSALSMGP FVPFIMRCGH SPVYHSREMA ARALVPFVMI DHIPNTIRSL LSTLPSCTDQ CFRQNHIHGT LLQVFHLLQA YSDSKHGTNS DFQHELTDIT VCTKAKLWLA KRQNPCLVTR AVYIDILFLL TCCLNRSAKD NQPVLESLGF WEEVRGIISG SELITGFPWA FKVPGLPQYL QSLTRLAIAA VWAAAAKSGE RETNVPISFS QLLESAFPEV RSLTLEALLE KFLAAASGLG EKGVPPLLCN MGEKFLLLAM KENHPECFCK ILKILHCMDP GEWLPQTEHC VHLTPKEFLI WTMDIASNER SEIQSVALRL ASKVISHHMQ TCVENRELIA AEL (59-400 aa encoded by BC025773)
Target Information
THADA (thyroid adenoma associated), also known as GITA, is a 1,953 amino acid protein that is expressed in testis, thyroid, pancreas, stomach and small intestine. Chromosomal aberrations in the gene encoding THADA are associated with benign thyroid adenomas, suggesting a potential role for THADA in tumorigenesis. The THADA gene maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: death receptor-interacting protein; Gene inducing thyroid adenomas protein; Thyroid adenoma-associated protein; Thyroid adenoma-associated protein homolog; tRNA (32-2'-O)-methyltransferase regulator THADA
Gene Aliases: 6530405K19; A930021O22; ARMC13; AU019899; BC052885; GITA; KIAA1767; RGD1560519; THADA
UniProt ID: (Human) Q6YHU6, (Mouse) A8C756
Entrez Gene ID: (Human) 63892, (Rat) 313865, (Mouse) 240174
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