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Product Details
PA5-57193
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human THADA. Recombinant protein control fragment (Product #RP-102654).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2648423
Product Specific Information
Immunogen sequence: MLCQLLPMQP VPESSDGLLT VEQVKEIGDY FKQHLLQSRH RGAFELAYTG FVKLTEVLNR CPNVSLQKLP EQWLWSVLEE IKCSDPSSKL CATR
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.
Target Information
THADA (thyroid adenoma associated), also known as GITA, is a 1,953 amino acid protein that is expressed in testis, thyroid, pancreas, stomach and small intestine. Chromosomal aberrations in the gene encoding THADA are associated with benign thyroid adenomas, suggesting a potential role for THADA in tumorigenesis. The THADA gene maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: death receptor-interacting protein; Gene inducing thyroid adenomas protein; Thyroid adenoma-associated protein; tRNA (32-2'-O)-methyltransferase regulator THADA
Gene Aliases: ARMC13; GITA; KIAA1767; THADA
UniProt ID: (Human) Q6YHU6
Entrez Gene ID: (Human) 63892
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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