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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • THAP12 Antibodies

          Invitrogen

          THAP12 Polyclonal Antibody

          View all (7) THAP12 antibodies
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          Datasheet
          Protocols
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          Cite THAP12 Polyclonal Antibody

          • Antibody Testing Data (2)
          THAP12 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          THAP12 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          THAP12 Antibody (PA5-52604) in ICC/IF

          Immunofluorecent analysis of THAP12 in human cell line U-2 OS using THAP12 Polyclonal Antibody (Product # PA5-52604). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          THAP12 Antibody in Immunocytochemistry (ICC/IF)
          THAP12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-52604

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human THAP12. Recombinant protein control fragment (Product #RP-89877).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2648425

          Product Specific Information

          Immunogen sequence: NPHSRHRKRI KELSEDEIRT LKQKKIDETS EQEQKHKETN NSNAQNPSEE EGEGQDEDIL PLTLEEKENK EYLKSLFEIL ILMGKQNIPL DGHEADEIPE GLFTPDNFQA LLECRINSGE EVLRKRFE

          Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

          Target Information

          Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 52 kDa repressor of the inhibitor of the protein kinase; 58 kDa interferon-induced protein kinase-interacting protein; Death-associated protein 4; inhibitor of protein kinase PKR; interferon-inducible, double stranded RNA dependent inhibitor, protein-kinase; P52rIPK; p58IPK-interacting protein; P58IPK-regulatory protein; protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor); testicular tissue protein Li 133; THAP domain-containing protein 0; THAP domain-containing protein 12

          View more View less

          Gene Aliases: 2900052B10Rik; DAP4; P52RIPK; PRKRIR; Rpkrir; THAP0; THAP12

          View more View less

          UniProt ID: (Mouse) Q9CUX1, (Human) O43422

          View more View less

          Entrez Gene ID: (Rat) 308845, (Mouse) 72981, (Human) 5612

          View more View less

          Function(s)
          nucleic acid binding protein dimerization activity DNA binding metal ion binding RNA polymerase II transcription factor activity, sequence-specific DNA binding protein binding
          Process(es)
          regulation of transcription from RNA polymerase II promoter response to stress signal transduction negative regulation of cell proliferation biological_process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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