Proteintech

THOC1 Polyclonal Antibody

THOC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 5

THOC1 Antibody (10920-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human colon cancer using 10920-1-AP (THOC1 antibody) at dilution of 1:100 (under 10x lens).

THOC1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10920-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 11 publications 11 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

THOC1 Fusion Protein Ag1352 (291-657 aa encoded by BC010381)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody recognizes the 84 kDa THOC1 protein.

Immunogen sequence: TGGEHVYFA KFLTSEKLMD LQLSDSNFRR HILLQYLILF QYLKGQVKFK SSNYVLTDEQ SLWIEDTTKS VYQLLSENPP DGERFSKMVE HILNTEENWN SWKNEGCPSF VKERTSDTKP TRIIRKRTAP EDFLGKGPTK KILMGNEELT RLWNLCPDNM EACKSETREH MPTLEEFFEE AIEQADPENM VENEYKAVNN SNYGWRALRL LARRSPHFFQ PTNQQFKSLP EYLENMVIKL AKELPPPSEE IKTGEDEDEE DNDALLKENE SPDVRRDKPV TGEQIEVFAN KLGEQWKILA PYLEMKDSEI RQIECDSEDM KMRAKQLLVA WQDQEGVHAT PENLINALNK SGLSDLAESL TNDNETNS (291-657 aa encoded by BC010381)

Target Information

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Is Nrf2 Behind Endogenous Neuroprotection of the Hippocampal CA2-4,DG Region?

Molecular neurobiology

Lewczuk A,Zablocka B,Beresewicz-Haller M

Wed Mar 01 00:00:00 UTC 2023

Integrative Analysis Revealed LINC00847 as a Potential Target of Tumor Immunotherapy.

Applied biochemistry and biotechnology

Chen X,Zhang L

Sun Oct 01 00:00:00 UTC 2023

Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.

Molecular cancer research : MCR

Liao X,Li Z,Zheng H,Qian W,Zhang S,Chen S,Li X,Tang M,Xu Y,Yu R,Li M,Song L,Li J

Wed Jul 05 00:00:00 UTC 2023

TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus.

PLoS pathogens

Zhao L,Liu Q,Huang J,Lu Y,Zhao Y,Ping J

Thu Sep 01 00:00:00 UTC 2022

TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus.

PLoS pathogens

Zhao L,Liu Q,Huang J,Lu Y,Zhao Y,Ping J

Thu Sep 01 00:00:00 UTC 2022

Bioactive peptide inhibits acute myeloid leukemia cell proliferation by downregulating ALKBH5-mediated m⁶A demethylation of EIF4EBP1 and MLST8 mRNA.

Cellular oncology (Dordrecht, Netherlands)

Zhang L,Su X

Wed Jun 01 00:00:00 UTC 2022

Cytoplasmic Clusterin Suppresses Lung Cancer Metastasis by Inhibiting the ROCK1-ERK Axis.

Cancers

Huang S,Li X,Gu W,Li X,Zhao J,Wu J,Cai J,Feng X,Tao T

Tue May 17 00:00:00 UTC 2022

Cytoplasmic Clusterin Suppresses Lung Cancer Metastasis by Inhibiting the ROCK1-ERK Axis.

Cancers

Huang S,Li X,Gu W,Li X,Zhao J,Wu J,Cai J,Feng X,Tao T

Tue May 17 00:00:00 UTC 2022

Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.

eLife

Ogino T,Matsunaga N,Tanaka T,Tanihara T,Terajima H,Yoshitane H,Fukada Y,Tsuruta A,Koyanagi S,Ohdo S

Fri Apr 23 00:00:00 UTC 2021

Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.

Journal of experimental & clinical cancer research : CR

Liu S,Chen L,Chen H,Xu K,Peng X,Zhang M

Fri Feb 12 00:00:00 UTC 2021

TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.

Cancer letters

Liu SL,Lin HX,Lin CY,Sun XQ,Ye LP,Qiu F,Wen W,Hua X,Wu XQ,Li J,Song LB,Guo L

Mon Aug 28 00:00:00 UTC 2017

Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.

Biochemical and biophysical research communications

Liu C,Yue B,Yuan C,Zhao S,Fang C,Yu Y,Yan D

Mon Mar 21 00:00:00 UTC 2016

Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.

Biochemical and biophysical research communications

Liu C,Yue B,Yuan C,Zhao S,Fang C,Yu Y,Yan D

Mon Mar 21 00:00:00 UTC 2016

Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.

Biochemical and biophysical research communications

Liu C,Yue B,Yuan C,Zhao S,Fang C,Yu Y,Yan D

Mon Mar 21 00:00:00 UTC 2016

Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.

Biochemical and biophysical research communications

Liu C,Yue B,Yuan C,Zhao S,Fang C,Yu Y,Yan D

Mon Mar 21 00:00:00 UTC 2016

The suppression of thoc1 in cancer cell apoptosis mediated by activated macrophages is nitric oxide-dependent.

Biochemical pharmacology

Lin YS,Lin CH,Huang LD,Chao T,Kuo CD,Hung LC,Wong FH,Lin CC,Fu SL

Mon Jul 15 00:00:00 UTC 2013

The suppression of thoc1 in cancer cell apoptosis mediated by activated macrophages is nitric oxide-dependent.

Biochemical pharmacology

Lin YS,Lin CH,Huang LD,Chao T,Kuo CD,Hung LC,Wong FH,Lin CC,Fu SL

Mon Jul 15 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: hTREX84; Nuclear matrix protein p84; p84N5; THO complex subunit 1; tho1

View more View less

Gene Aliases: 3110002N20Rik; AW107452; HPR1; LRRGT00070; NMP-84; P84; P84N5; THOC1

View more View less

UniProt ID: (Human) Q96FV9, (Mouse) Q8R3N6

View more View less

Entrez Gene ID: (Human) 9984, (Mouse) 225160, (Rat) 291797

View more View less

Function(s)

DNA binding RNA binding protein binding

Process(es)

regulation of DNA recombination termination of RNA polymerase II transcription RNA processing RNA export from nucleus mRNA export from nucleus apoptotic process signal transduction RNA splicing mRNA 3'-end processing replication fork processing regulation of DNA-templated transcription, elongation positive regulation of DNA-templated transcription, elongation viral mRNA export from host cell nucleus negative regulation of isotype switching to IgA isotypes negative regulation of DNA damage checkpoint transcription, DNA-templated regulation of transcription, DNA-templated mRNA processing transport regulation of apoptotic process mRNA transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

THOC1 Polyclonal Antibody

THOC1 Antibody (10920-1-AP) in IHC (P)

Product Details

10920-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!