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THOC2 Polyclonal Antibody

THOC2 Antibody in Immunocytochemistry (ICC/IF)

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THOC2 Antibody (55178-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 55178-1-AP (THOC2 antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG.

THOC2 Antibody in Immunoprecipitation (IP)

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Product Details

55178-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded protein interacts with the THOC1 protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Clinical and functional characterization of recurrent missense variants implicated in THOC6-related intellectual disability.

Human molecular genetics

Mattioli F,Isidor B,Abdul-Rahman O,Gunter A,Huang L,Kumar R,Beaulieu C,Gecz J,Innes M,Mandel JL,Piton A

Fri Mar 15 00:00:00 UTC 2019

Clinical and functional characterization of recurrent missense variants implicated in THOC6-related intellectual disability.

Human molecular genetics

Mattioli F,Isidor B,Abdul-Rahman O,Gunter A,Huang L,Kumar R,Beaulieu C,Gecz J,Innes M,Mandel JL,Piton A

Fri Mar 15 00:00:00 UTC 2019

Murine leukemia virus uses TREX components for efficient nuclear export of unspliced viral transcripts.

Viruses

Sakuma T,Tonne JM,Ikeda Y

Mon Mar 10 00:00:00 UTC 2014

Murine leukemia virus uses TREX components for efficient nuclear export of unspliced viral transcripts.

Viruses

Sakuma T,Tonne JM,Ikeda Y

Mon Mar 10 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: hTREX120; mental retardation, X-linked 12; mental retardation, X-linked 35; THO complex subunit 2; Tho2

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Gene Aliases: CXorf3; dJ506G2.1; hTREX120; MRX12; MRX35; THO2; THOC2

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UniProt ID: (Human) Q8NI27

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Entrez Gene ID: (Human) 57187

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Function(s)

RNA binding protein binding

Process(es)

termination of RNA polymerase II transcription RNA export from nucleus mRNA export from nucleus RNA splicing poly(A)+ mRNA export from nucleus mRNA 3'-end processing viral mRNA export from host cell nucleus neuron development generation of neurons

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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THOC2 Polyclonal Antibody

THOC2 Antibody (55178-1-AP) in ICC/IF

Product Details

55178-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

Bioinformatics

Performance Guarantee

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