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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TIA-1 Antibodies

          Proteintech

          TIA1 Polyclonal Antibody

          57 References
          View all (45) TIA-1 antibodies

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          Datasheet
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          Datasheet
          Protocols
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          Cite TIA1 Polyclonal Antibody

          • Antibody Testing Data (10)
          TIA1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          TIA1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          TIA1 Antibody (12133-2-AP) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed L02 cells using TIA1 antibody (Product # 12133-2-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), 594-CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          TIA1 Antibody in Immunocytochemistry (ICC/IF)
          TIA1 Antibody in Immunocytochemistry (ICC/IF)
          TIA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIA1 Antibody in Western Blot (WB)
          TIA1 Antibody in Western Blot (WB)
          TIA1 Antibody in Western Blot (WB)
          TIA1 Antibody in Western Blot (WB)
          TIA1 Antibody in Western Blot (WB)
          TIA1 Antibody in Immunoprecipitation (IP)

          Product Details

          12133-2-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:4,000
          View 27 publications 27 publications

          Immunohistochemistry (IHC)

          -
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:200
          View 24 publications 24 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication

          ChIP assay (ChIP)

          -
          View 1 publication 1 publication

          RNA Immunoprecipitation (RIP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          TIA1 Fusion Protein Ag2778 (1-214 aa encoded by BC015944)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.23 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MEDEMPKTL YVGNLSRDVT EALILQLFSQ IGPCKNCKMI MDTAGNDPYC FVEFHEHRHA AAALAAMNGR KIMGKEVKVN WATTPSSQKK DTSSSTVVST QRSQDHFHVF VGDLSPEITT EDIKAAFAPF GRISDARVVK DMATGKSKGY GFVSFFNKWD AENAIQQMGG QWLGGRQIRT NWATRKPPAP KSTYECRCIG EEKEMWNFGE KYARF (1-214 aa encoded by BC015944)

          Target Information

          Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Cytotoxic granule associated RNA binding protein TIA1; cytotoxic granule-associated RNA binding protein 1; cytotoxic granule-associated RNA-binding protein 1; Nucleolysin TIA-1; Nucleolysin TIA-1 isoform p40; p40 TIA 1; p40-TIA-1; p40-TIA-1 (containing p15-TIA-1); RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA 1; TIA-1; TIA1 protein; TIAL1; TIAR

          View more View less

          Gene Aliases: 2310050N03Rik; AI256674; mTIA-1; Tia; TIA-1; TIA1; WDM

          View more View less

          UniProt ID: (Human) P31483, (Mouse) P52912

          View more View less

          Entrez Gene ID: (Human) 7072, (Rat) 312510, (Mouse) 21841

          View more View less

          Function(s)
          nucleotide binding protein binding poly(A) binding AU-rich element binding poly(A) RNA binding nucleic acid binding RNA binding
          Process(es)
          apoptotic process fibroblast growth factor receptor signaling pathway negative regulation of translation negative regulation of cytokine biosynthetic process regulation of mRNA splicing, via spliceosome protein localization to cytoplasmic stress granule positive regulation of epithelial cell apoptotic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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