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TIGAR Antibody (MA5-55720) in WB
Western blot analysis of TIGAR in 15 µg of HeLa. Sample was run on 6-18% SDS-PAGE under reducing conditions, blotted onto nitrocellulose membrane, and peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. TIGAR band was visualized using ECL Western Blotting Substrate. Incubation with primary TIGAR monoclonal antibody (Product # MA5-55720) at a dilution of 1 µg/mL was used.
Product Details
MA5-55720
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
K92034_1F2
Immunogen
Recombinant human TIGAR (immunogen range is 11-270).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_3667952
Product Specific Information
Sequence of this protein is as follows: HGETRFNKEK IIQGQGVDEP LSETGFKQAA AAGIFLNNVK FTHAFSSDLM RTKQTMHGIL ERSKFCKDMT VKYDSRLRER KYGVVEGKAL SELRAMAKAA REECPVFTPP GGETLDQVKM RGIDFFEFLC QLILKEADQK EQFSQGSPSN CLETSLAEIF PLGKNHSSKV NSDSGIPGLA ASVLVVSHGA YMRSLFDYFL TDLKCSLPAT LSRSELMSVT PNTGMSLFII NFEEGREVKP TVQCICMNLQ DHLNGLTETR
Target Information
This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fructose-2,6-bisphosphatase TIGAR; fructose-2,6-bisphosphate 2-phosphatase; probable fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase; transactivated by NS3TP2 protein
Gene Aliases: C12orf5; FR2BP; TIGAR
UniProt ID: (Human) Q9NQ88
Entrez Gene ID: (Human) 57103
response to ischemia
fructose 2,6-bisphosphate metabolic process
autophagy
apoptotic process
cellular response to DNA damage stimulus
response to xenobiotic stimulus
response to gamma radiation
positive regulation of cardiac muscle cell apoptotic process
dephosphorylation
fructose 1,6-bisphosphate metabolic process
negative regulation of programmed cell death
regulation of pentose-phosphate shunt
positive regulation of DNA repair
negative regulation of glycolytic process
intestinal epithelial cell development
cellular response to cobalt ion
cellular response to hypoxia
negative regulation of neuron death
negative regulation of macromitophagy
regulation of response to DNA damage checkpoint signaling
positive regulation of hexokinase activity
negative regulation of glucose catabolic process to lactate via pyruvate
negative regulation of reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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