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          • Primary Antibodies ›
          • TIGIT Antibodies

          Bethyl Laboratories

          TIGIT Recombinant Rabbit Monoclonal Antibody (BLR047F)

          View all (74) TIGIT antibodies
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          Datasheet
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          Cite TIGIT Recombinant Rabbit Monoclonal Antibody (BLR047F)

          • Antibody Testing Data (7)
          TIGIT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          TIGIT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          TIGIT Antibody (A700-047) in IHC (P)

          Detection of human TIGIT (red) by immunohistochemistry. Sample: FFPE section of human tonsil. Antibody: Rabbit anti-TIGIT recombinant monoclonal antibody [BLR047F] (Product # A700-047) (lot 1) used at 1:250. Secondary: HRP-conjugated goat anti-rabbit IgG (A120-501P). Substrate: Opal™. Counterstain: DAPI (blue). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          TIGIT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIGIT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIGIT Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TIGIT Antibody in Western Blot (WB)
          TIGIT Antibody in Western Blot (WB)
          TIGIT Antibody in Western Blot (WB)
          TIGIT Antibody in Flow Cytometry (Flow)

          Product Details

          A700-047

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100 - 1:500
          -

          Flow Cytometry (Flow)

          2 µL per 1 x 10^6 cells
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          BLR047F

          Immunogen

          Peptide representing a region between residue 194 and the C-terminus (residue 244) of human T-cell immunoreceptor with Ig and ITIM domains precursor (TIGIT).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1000 µg/mL

          Purification

          purified

          Storage buffer

          BBS, pH 7.8 to 8.6

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; Washington University cell adhesion molecule

          View more View less

          Gene Aliases: TIGIT; VSIG9; VSTM3; WUCAM

          View more View less

          UniProt ID: (Human) Q495A1

          View more View less

          Entrez Gene ID: (Human) 201633

          View more View less

          Function(s)
          receptor activity receptor binding protein binding protein homodimerization activity cell adhesion molecule binding
          Process(es)
          homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell recognition negative regulation of interleukin-12 production positive regulation of interleukin-10 production negative regulation of T cell activation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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